TO THE EDITOR: We have read with interest the recently published work by Wölnerhanssen et al. (7) entitled “Gut hormone secretion, gastric emptying, and glycemic responses to erythritol and xylitol in lean and obese subjects”. The authors demonstrated the ability of erythritol and xylitol to induce gut hormone secretion and gastric emptying retardation with no impact on glycemic and insulinemic...

PURPOSE The aim was to evaluate the effect of maternal use of chewing gums containing xylitol, chlorhexidine/xylitol or fluoride on the prevalence of mutans streptococci (MS) in the mothers' 18-month-old offsprings. MATERIALS AND METHODS After screening 416 women with newborn babies, 173 mothers with high counts of salivary MS were randomly assigned into three experimental chewing gum groups ...

Xylitol dehydrogenase (XDH) was purified from the cytoplasmic fraction of Gluconobacter oxydans ATCC 621. The purified enzyme reduced D-xylulose to xylitol in the presence of NADH with an optimum pH of around 5.0. Based on the determined NH2-terminal amino acid sequence, the gene encoding xdh was cloned, and its identity was confirmed by expression in Escherichia coli. The xdh gene encodes a po...

This study reports an industrially applicable non-sterile xylitol fermentation process to produce xylitol from a low-cost feedstock like corn cob hydrolysate as pentose source without any detoxification. Different immobilization matrices/mediums (alginate, polyvinyl alcohol, agarose gel, polyacrylamide, gelatin, and κ-carrageenan) were studied to immobilize Candida tropicalis NCIM 3123 cells fo...

background:dental caries is associated with oral pathogenes and streptococcus mutans (s. mutans)is one of the primary cariogenic organisms. the aim of this clinical study was to evaluate the effect of sugar free chewing gum containing casein phosphopeptide-amorphous calcium phosphate(cpp-acp) and xylitol on salivary streptococcus mutan.   m aterials and methods: 60 dental students, who voluntee...

The production of xylitol from concentrated synthetic xylose solutions (S(o) = 130-135 g/L) by Debaryomyces hansenii was investigated at different pH and temperature values. At optimum starting pH (pH(o) = 5.5), T = 24 degrees C, and relatively low starting biomass levels (0.5-0.6 g(x)/L), 88% of xylose was utilized for xylitol production, the rest being preferentially fermented to ethanol (10%...

Reducing xylitol formation is necessary in engineering xylose utilization in recombinant Saccharomyces cerevisiae for ethanol production through xylose reductase/xylitol dehydrogenase pathway. To balance the expression of XYL1 and mutant XYL2 encoding xylose reductase (XR) and NADP(+)-dependent xylitol dehydrogenase (XDH), respectively, we utilized a strategy combining chassis selection and dir...

Xylitol, a five-carbon sugar alcohol, has similar sweetening power as sucrose. It has unique pharmacological properties such as prevention of tooth decay and ear infection in children; it is used as a sugar substitute for diabetic patients and in parenteral application to trauma patients. Xylitol is increasingly being used in chewing gums, candy, soft drinks, ice cream and oral hygiene products...

Xylose-rich sawdust hydrolysate can be an economic substrate for the enzymatic production of xylitol, a specialty product. It is important to identify the process factors influencing xylitol production. This research aimed to screen the parameters significantly affecting bioxylitol synthesis from wood sawdust by xylose reductase (XR). Enzymatic bioxylitol production was conducted to estimate th...

Xylitol is effective as a non-cariogenic sugar substitute. Habitual xylitol consumption appears to select for mutans streptococci (MS) with impaired adhesion properties, i.e., they shed easily to saliva from plaque. One hundred sixty-nine mother-child pairs participated in a two-year study exploring whether the mothers' xylitol consumption could be used to prevent mother-child transmission of m...