xenograft models

نتایج جستجو برای: xenograft models

تعداد نتایج: 924797 فیلتر نتایج به سال:

Assessment of Antitumor Activity for Tumor Xenograft Studies Using Exponential Growth Models

Journal: :Journal of Biopharmaceutical Statistics 2011

متن کامل

SPA: A Quantitation Strategy for MS Data in Patient-derived Xenograft Models

Journal: :Genomics, Proteomics & Bioinformatics 2021

متن کامل

Systematic Analysis of a Xenograft Mice Model for KSHV+ Primary Effusion Lymphoma (PEL)

2014

Lu Dai Jimena Trillo-Tinoco Lihua Bai Baoli Kang Zengguang Xu Xiaofei Wen Luis Del Valle Zhiqiang Qin

Kaposi's sarcoma-associated herpesvirus is the causative agent of primary effusion lymphoma (PEL), which arises preferentially in the setting of infection with human immunodeficiency virus (HIV). Even with standard cytotoxic chemotherapy, PEL continues to cause high mortality rates, requiring the development of novel therapeutic strategies. PEL xenograft models employing immunodeficient mice ha...

متن کامل

Gene expression profile identifies tyrosine kinase c-Met as a targetable mediator of antiangiogenic therapy resistance.

Journal: :Clinical cancer research : an official journal of the American Association for Cancer Research 2013

Arman Jahangiri Michael De Lay Liane M Miller W Shawn Carbonell Yu-Long Hu Kan Lu Maxwell W Tom Jesse Paquette Taku A Tokuyasu Sean Tsao Roxanne Marshall Arie Perry Kirsten M Bjorgan Myriam M Chaumeil Sabrina M Ronen Gabriele Bergers Manish K Aghi

PURPOSE To identify mediators of glioblastoma antiangiogenic therapy resistance and target these mediators in xenografts. EXPERIMENTAL DESIGN We conducted microarray analysis comparing bevacizumab-resistant glioblastomas (BRG) with pretreatment tumors from the same patients. We established novel xenograft models of antiangiogenic therapy resistance to target candidate resistance mediator(s). ...

متن کامل