نتایج جستجو برای: xenograft

تعداد نتایج: 23157  

Journal: :Cancer and Metabolism 2021

Abstract Background Sulfasalazine (SSZ) is widely known as an xCT inhibitor suppressing CD44v9-expressed cancer stem-like cells (CSCs) being related to redox regulation. Cholangiocarcinoma (CCA) has a high recurrence rate and no effective chemotherapy. A recent report revealed levels of CD44v9-positive in CCA patients. Therefore, combination drugs could prove suitable strategy for treatment via...

Journal: :Al-Azhar Dental Journal for Girls 2021

Purpose: I-PRF was found to be effective in wound healing and bone regeneration, thus the purpose of this study carried out evaluate clinically radiographically Injectable Platelet Rich Fibrin (I-PRF) around immediate dental implant esthetic zone with xenograft. Material methods: A total twelve patients unrestorable tooth/teeth were involved study. They randomly divided into two groups; Group I...

Journal: :Journal of pediatric orthopedics 2017
Jason Rhodes Alfred Mansour Allison Frickman Breanna Pritchard Katherine Flynn Zhaoxing Pan Frank Chang Nancy Miller

BACKGROUND The Evan's calcaneal lengthening osteotomy is a treatment method for spastic flatfoot deformity in patients with cerebral palsy that fail nonoperative measures. Autograft and allograft have been reported as potential graft choices. Bovine xenograft has been introduced as an alternative, but limited human data exists supporting its efficacy. This study compares the long-term results o...

2011
Michael P. Kim Jason B. Fleming Huamin Wang James L. Abbruzzese Woonyoung Choi Scott Kopetz David J. McConkey Douglas B. Evans Gary E. Gallick

BACKGROUND Multiple studies in recent years have identified highly tumorigenic populations of cells that drive tumor formation. These cancer stem cells (CSCs), or tumor-initiating cells (TICs), exhibit properties of normal stem cells and are associated with resistance to current therapies. As pancreatic adenocarcinoma is among the most resistant human cancers to chemo-radiation therapy, we soug...

Journal: :Theranostics 2021

Glioblastoma (GBM) is the most lethal primary brain tumor in adults with a median survival of around 15 months. A potential treatment strategy involves targeting glioma stem-like cells (GSCs) that are able to initiate, maintain, and repopulate mass. Here, we identify ACT001, parthenolide derivative, GSCs through regulation adipocyte enhancer binding protein 1 (AEBP1) signaling. Methods: The eff...

Journal: :Journal of clinical pathology 1981
D Raghavan E Heyderman P Monaghan J Gibbs E Ruoslahti M J Peckham A M Neville

A xenograft line, HX 53, has been established in immune-suppressed mice from a specimen of a lymph node metastasis in a patient with a histological diagnosis of seminoma but with markedly raised circulating levels of alpha-fetoprotein. Histological, immunocytochemical, and ultrastructural studies of this xenograft line have suggested that a solid variant of yolk sac carcinoma may exist, which m...

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