The hierarchical morphology of xanthan solutions is analyzed by light and neutron scattering in a broad range of concentrations in order to connect their morphology to their well-documented dynamic properties. Static light scattering inside the semidilute regime is dominated by the form factor of individual xanthan chains while at higher concentrations chain interconnections appear to modify th...

Blended cornstarch–xanthan gum systems were optimized for thickening of cocoa syrups. For this purpose the sensory (whole and partial), textural (force of penetration, adhesiveness and stringiness) and rheological properties (flow curves as well as viscosity/time and viscosity/temperature relationships) of cocoa syrups were studied. Flow curves were described by rheological model of Casson, whi...

xanthomonas campestris was used for producing xanthan gum using date syrup, prepared from low quality dates, as a substrate. fermentation was carried out with date syrup and sucrose syrup at 28 ˚c and ph 6.8 in a rotary benmarin shaker (240 rpm). the effect of fermentation period (24, 48, 72, 96 and 120 h) on xanthan gum production was studied. the results showed that eps concentration increase...

The objective of this study was to design and evaluate oral sustained drug delivery system for Metoprolol succinate using natural hydrophilic gums such as karaya gum and xanthan gum as a release modifier. Nine batches were prepared by using karaya gum (KG) and xanthan gum (XG) in concentration of 15%, 20% and 25% alone and in combination of 2:8. Matrix tablets were prepared by wet granulation m...

The aim of the present study was to apply design of experiment (DOE) to optimize floating drug delivery of tapentadol hydrochloride. Tapentadol hydrochloride is a synthetic opioid used as a centrally acting analgesic and effective in both experimental and clinical pain. The half-life of the drug is about 4 hours and oral dose is 50 to 250 mg twice a day. For optimization 3(2) full factorial des...

Xanthan biopolymer has been produced by single-stage continuous ferment~ tion with Xanthomonas campestris NRRL B-1459 in a medium of glucose, minerals, distillers' solubles, and urea for as long as 20 days. At the highest dilution rate studied (D = 0.0285 hr-1), the steady state rate of xanthan production was 0.36 g/kg/hr and ·the steady state yield, basis glucose consumed, was 68%. Observation...

We study the assembly of inert and living colloids in a two-phase water-water system that provides an environment that can sustain bacteria, providing a new structure with rich potential to confine and structure microbial communities. The water-water system, formed via phase separation of a casein and xanthan mixture, forms a 3-D structure of coexisting casein-rich and xanthan-rich phases. Fluo...

The aim of this study was to investigate the influence of pH, buffer species and ionic strength on the release mechanism of Glipizide (G) from matrix tablets containing chitosan and xanthan gum prepared by a hot-melt extrusion process. The release mechanisms were controlled by the solubility and ionic properties of the polymers. All directly compressed (DC) tablets prepared in this study also e...

BACKGROUND Natural gums are polymers widely used as excipients in drug formulation. Polymer extraction and formulation processing methods could significantly affect formulation characteristics. OBJECTIVES To evaluate different methods of gum extraction and the effect of different compression methods on the mechanical and release properties of tramadol hydrochloride matrix tablets incorporatin...