BACKGROUND Pathologic analysis of deep tissue obtained during debridement of venous ulcers is often unnoticed in its importance. We previously reported pathologic findings on 139 patients with venous ulcers. The objective of this study was to correlate the pathologic findings in venous ulcers with wound healing to establish a negative margin for debridement. STUDY DESIGN Consecutive patients ...

We report a case of posttraumatic skin and soft-tissue infection in a patient with a left thigh wound after a traffic accident. Pseudomonas fulva was isolated from a wound aspirate and was identified to the species level by Maldi-tof. The patient responded to drainage, debridement of wound, and two weeks of intravenous antibiotic therapy. Follow-up after 3 weeks was satisfactory with healthy co...

PURPOSE To investigate the effect of the Cdk5 inhibitor olomoucine on corneal debridement wound healing in vivo. METHODS Corneal debridement wounds of 1.5 mm were made on the ocular surface of CD-1 mice. A 20 microl drop of 15 microM olomoucine in 1% DMSO was applied to the wound area immediately after wounding and again after 6 h. Control mice received identical applications of 1% DMSO. Mice...

Soldiers wounded in modern warfare present with extensive and complicated acute wounds, confounded by an overwhelming inflammatory response. The pathophysiology of acute wounds is unknown and timing of wound closure remains subjective. Collagen gene expression profiles are presented for 24 patients. Impaired healing wounds showed a twofold decrease in the up-regulation of COL1A1 and COL3A1 gene...

Aeromonas hydrophila is a rare human pathogen. Reports of zoonotic infection developing after large feline bites are even rarer. We are documenting the first case of human wound infection with A. hydrophila following a tiger bite. The patient responded well following wound debridement, secondary suturing and combination antibiotic therapy.

INTRODUCTION Pedal Wounds secondary to complications related to Diabetes Mellitus Wounds related to diabetes mellitus are multifactorial in etiology. Primary factors contributing to chronic diabetic foot ulceration include peripheral neuropathy and peripheral vascular disease. Secondary factors including limited joint mobility, neuropathic osteoarthropathy (Charcot foot), and a depressed immune...

UNLABELLED The aim of the study was to present experience of doctors from the Center for Burns Treatment in Siemianowice Śląskie who use a Versajet system. MATERIAL AND METHODS Debridement with the use of a water jet was applied in 70 patients with IIb° /III° thermal burns in the period between 2009-2013. The corresponding evaluation involved duration of operation, locations, wound surfaces a...

antimicrobial therapy remains to be the most important method of wound infection treatment. systemically administered antimicrobials may not achieve therapeutic level in wound. on the other hand, in the absence of surgical debridement (due to any reason), most topically applied antimicrobials cannot penetrate the wound in therapeutic amount due to the presence of eschar. burn eschar is a protei...

The case is reported of an open injury of the right arm sustained during a parachute jump. The fracture was managed in the usual way with wound debridement, wound irrigation, skeletal stabilisation, and reconstruction of the soft tissues. Good shoulder and elbow function were achieved. The combined effort of an orthopaedic trauma surgeon and plastic surgeon is essential to improve outcomes in s...