Osteoarthritis (OA) is one of the most common musculoskeletal disorders all over the world. Available anti-arthritic medications have only partial efficacy and their long-term use is associated with adverse events. Elaeagnus Angustifolia (EA) is a medicinal plant with analgesic and anti-inflammatory properties. The present study evaluated the impact of two doses of EA extract compared with ibup...

BACKGROUND Osteoarthritis (OA) is a chronic disease, usually characterized by pain, which is associated with reduced muscle strength, disability and progressive loss of function. However, the pain influence over proprioception and motor behaviour remains unclear. Thus, the purpose of the study was to identify the levels of pain, the proprioceptive acuity and the pattern of muscle recruitment du...

PURPOSE To compare the results of focal metallic resurfacing with biologic procedures in patients more than 35 years of age with isolated, full thickness defects of the femoral condyle. METHODS A total of 61 patients met the selection criteria resulting in 30 patients treated with biological procedures, including debridement, microfracture, osteochondral autograft transplantation, osteochondr...

BACKGROUND There is growing concern about the use of opioids prior to total knee arthroplasty (TKA), and research has suggested that preoperative opioid use may lead to worse pain outcomes following surgery. We evaluated the pain relief achieved by TKA in patients who had and those who had not used opioids use before the procedure. METHODS We augmented data from a prospective cohort study of ...

Purpose: To determine whether enablement was a moderator of the effect chronic back and knee pain on health-related quality life (HRQOL). Methods: This cross-sectional study 1319 Chinese primary care patients with problems who completed Patient Enablement Instrument-2 (PEI-2), Western Ontario McMaster University Osteoarthritis Index (WOMAC), Pain Rating Scale (PRS). Multivariable regression exa...

Objective: Intra-articular platelet-rich plasma PRP (platelet-rich plasma) treatment can be applied at an early stage of Gonarthrosis in addition to medical treatment. There is no consensus the literature regarding dose interval PRP. Our aim this study compare short-term clinical results three doses administered one and two-week intervals early-stage Gonarthrosis. Material Methods: Three were k...

BACKGROUND Current use of prescribed or over the counter non-steroidal anti-inflammatory drugs (NSAIDs) for pain and osteoarthritis (OA) have untoward gastrointestinal and cardiovascular related side effects, as a result the need for a safe and effective alternative has become unequivocally crucial. METHOD A randomized, double blind, placebo and active controlled pilot study of a novel dual p...

introduction intra-articular injections of platelet rich plasma (prp) for the treatment of knee osteoarthritis have been shown to reduce pain and improve joint function. the aim of this study is to examine the joint function by adding intra-articular growth hormone to platelet rich plasma. this study was performed on the individuals with knee osteoarthritis and under ultrasound guidance. conclu...