Abstract Mantle plumes are typically considered secondary features of mantle convection, yet their surface effects over Earth's evolution may have been significant. We use 2‐D convection models to show that can in fact cause the termination a subduction zone. This extreme case plume‐slab interaction is found when slab readily weakened, for example, by damage‐type rheology, and subducting young....

background: the herpes simplex virus (hsv) ul41 gene product, virion host shutoff (vhs) protein, mediates the rapid degradation of both viral and cellular mrna. this ability suggests that vhs protein can be used as a suicide gene in cancer gene therapy applications. the recent reports have shown that the degradation of cellular mrna during herpes simplex infection is selective. rna containing a...