BACKGROUND A real-time electronic predictive model that identifies hospitalized heart failure (HF) patients at high risk for readmission or death may be valuable to clinicians and hospitals who care for these patients. METHODS An automated predictive model for 30-day readmission and death was derived and validated from clinical and nonclinical risk factors present on admission in 1372 HF hosp...

We investigate confidence intervals and inference for the instrumental variables model with weak instruments. Wald-based confidence intervals perform poorly in that the probability they reject the null is far greater than their nominal size. In the worst case, Wald-based confidence intervals always exclude the true parameter value. Confidence intervals based on the LM, LR, and Anderson-Rubin st...

abstract background: in iran gastric cancer is the second most common cancer and the most cause of death cancer, the aim of this study is provide map geographical distribution of gastric cancer and detect high risk cluster with use of space-time scan statistic. methods: this was an applied study. the data is provided from reports published by center for disease control office in ministry of hea...

The e¢ cient bootstrap methodology is developed for overidenti…ed moment conditions models with weakly dependent observation. The resulting bootstrap procedure is shown to be asymptotically valid and can be used to approximate the distributions of t-statistics, J statistic for overidentifying restrictions, and Wald, Lagrange multiplier and distance statistics for nonlinear hypotheses. The asymp...

Suppose that we have the density ß›y;Sfi of a model with the null hypothesis of the form H 0;S = S 0 . Let L›Sfi be the log-likelihood function of the model and  S be the MLE of S. Wald test is based on the very intuitive idea that we are willing to accept the null hypothesis when  S is close to S 0 . The distance between  S and S 0 is the basis of constructing the test statistic. On the oth...

It is important to investigate whether genetic susceptibility variants exercise the same effects in populations that are differentially exposed to environmental risk factors. Here, we assess the power of four two-stage case-control design strategies for assessing multiplicative gene-environment (G-E) interactions or for assessing genetic or environmental effects in the presence of G-E interacti...