Sleep is essential. Unfortunately, a significant portion of the population experiences altered sleep states that often result in a multitude of health-related issues. The regulation of sleep and sleep-wake cycles is an area of intense research, and many options for treatment are available. The following review summarizes the current understanding of normal and abnormal sleep-related conditions ...

RATIONALE The concept of a tonic drive activating respiratory muscle in wakefulness but not sleep has been an important and enduring notion in respiratory medicine, not least because it is useful in modeling sleep effects on breathing and understanding the pathogenesis of sleep-related breathing disorders such as obstructive sleep apnea. However, a neurotransmitter substrate mediating respirato...

STUDY OBJECTIVES Because sleep and wakefulness differ from each other by the amount of body movement, it has been claimed that the two states can be accurately distinguished by wrist actigraphy. Our objective was to test this claim in lengthy polysomnographic (psg) and actigraphic (acf) samples that included night and day components. DESIGN Fourteen healthy young (21-35 years) and old (70-72 ...

in this paper, considering the importance of incoming flow turbulence intensity into combustion chamber, tripping wire effect on the flow wake has been experimentally investigated within a linear compressor cascade. to do this, two wires were implemented along each blade and their effects on average velocity, turbulence intensity and vortices frequencies at reynolds number 45500 were accurately...

the shape of wake behind a wind turbine is normally assumed to have a hat shape for the models used in wind farm layout optimization purposes; however, it is know from experimental tests and numerical simulations that this is not a real assumption. in reality, the results of actual measurements and detailed numerical simulation show that the velocity in wake region has a s-shape profile. the pr...

My favourite Simon Armitage poem, ‘Homecoming’, begins, ‘Think, two things on their own and both at once’, tells, in brief, through juxtapositions of imagery, the story a subject, ‘you’, l...

We report some experiments undertaken to investigate the origin of ordered and chaotic laminar vortex streets behind circular cylinders at low Reynolds numbers. We made simultaneous measurements of near wake longitudinal velocity and cylinder lateral vibration amplitude spectra for cylinder Reynolds numbers in the range from 40 to 160. For a non-vibrating cylinder the velocity energy spectra co...

Obese Zucker rats have a narrower and more collapsible upper airway compared with lean controls, similar to obstructive sleep apnea (OSA) patients. Genioglossus (GG) muscle activity is augmented in awake OSA patients to compensate for airway narrowing, but the neural control of GG activity in obese Zucker rats has not been investigated to determine whether such neuromuscular compensation also o...

The recent literatures indicate that central nervous system (CNS) is highly vulnerable to systemic hyperthermia induced by whole body heating on conscious animals. In the present study, cerebral electrical activity or EEG (electroencephalogram) following exposure to high environmental heat has been studied in moving rats. Rats were divided into three group (i) acute heat stress-subjected to a s...