METHODS These studies were designed to assess whether wheat polyphenols (mainly ferulic acid [FA]) increased the very-long-chain omega-3 fatty acids (VLC n-3) [eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA)] in rats. Wheat aleurone (WA) was used as a dietary source of wheat polyphenols. Two experiments were performed; in the first one, the rats were fed WA or control pellets (CP) in...

The walls of Aspergillus nidulans conidia contain a green pigment that protects the spores from damage by ultraviolet light. At least two genes, wA and yA, are required for pigment synthesis: yA mutants produce yellow spores, wA mutants produce white spores, and wA mutations are epistatic to yA mutations. We cloned wA by genetic complementation of the wA3 mutation with a cosmid library containi...

We describe examples of wA gene inactivation (resulting in white conidiospores) obtained during transformation of Aspergillus nidulans. One wA- transformant was obtained by transformation with a prn+ plasmid of a strain with green conidia (wA+) which was unable to catabolize L-proline (prn-). This transformant contains a very large number of plasmid copies integrated at a single site inseparabl...

The purpose of this study was to examine the regulation of prosurvival factors heat shock factor 1 (HSF1) and breast cancer susceptibility gene 1 (BRCA1) by a natural withanolide withaferin A (WA) in triple negative breast cancer cell lines MDA-MB-231 and BT20. Western analysis was used to examine alternations in HSF1 and BRCA1 protein levels following WA treatment. A protein synthesis inhibito...

BACKGROUND The concept of work ability (WA) has a 30-year history in Finland, where it has been used extensively in occupational health (OH) research and practice. The extent to which WA has been integrated into UK OH practice is unclear. AIMS (i) To compare knowledge, understanding and use of WA among OH nurses and physicians in the UK and Finland and (ii) to identify factors that influence ...

Weighted automata (WA) are an important formalism to describe quantitative properties. Obtaining equivalent deterministic machines is a longstanding research problem. In this paper we consider WA with a set semantics, meaning that the semantics is given by the set of weights of accepting runs. We focus on multi-sequential WA that are defined as finite unions of sequential WA. The problem we add...

Waltonitone (WA), an ursane-type pentacyclic triterpene extracted from Gentiana waltonii Burkill, was recently appeared to exert anti-tumor effect. However, the biological underpinnings underlying the role of WA in hepatocellular carcinoma (HCC) cells have not been completely elucidated. Our previous report indicated that the FXR-regulated miR-22-CCNA2 pathway contributed to the progression and...

Let Wa be an irreducible affine Weyl group with W0 the associated Weyl group. The present paper is to study the second lowest two-sided cell Ωqr of Wa. Let nqr be the number of left cells of Wa in Ωqr. We conjecture that the equality nqr = 1 2 |W0| should always hold. When Wa is either e An−1, n > 2, or of rank 6 4, this equality can be verified by the existing data (see 0.3). Then the main res...

STRESZCZENIE Wstęp. Ce lem ba dań jest oce na sku tecz no ści le cze nia nie rów no ści koń czyn dol nych (nkd) blo ko wa niem chrzą stek wzro sto wych me to dą Phe mi ste ra na tle ak tu al nie sto so wa nych me tod epi fi zjo de zy oraz okre śle nie czyn ni ków mo gą cych mieć wpływ na wy nik koń co wy. Ma te riał i me to dy. Ana li zie pod da no 19 dziew cząt i 16 chłop ców ze śred nią wie k...