Entry of wild-type lentivirus equine infectious anemia virus (EIAV) into cells requires a low-pH step. This low-pH constraint implicates endocytosis in EIAV entry. To identify the endocytic pathway involved in EIAV entry, we examined the entry requirements for EIAV into two different cells: equine dermal (ED) cells and primary equine endothelial cells. We investigated the entry mechanism of sev...

PURPOSE Despite the goal of medical education, which is 'training to be a primary care physician,' only written examinations (WEs) generally have been used to assess medical student ability. We assessed clinical competence using the CPX (clinical performance examination), PA (portfolio assessment), VMA (video-monitoring assessment), CGD (case group discussion), and PCP (primary clinical practic...

With the dissemination of optical coherence tomography over the past two decades, the role of persistent vitreomacular adhesion (VMA) in the development of numerous macular pathologies - including idiopathic macular hole, vitreomacular traction syndrome, cystoid and diabetic macular edema, neovascularization in diabetic retinopathy and retinal vein occlusion, exudative age-related macular degen...

Intravenous administration of tritium-labeled 3,4-dihydroxyphenylalanine (dopa) to human subjects resulted in the labeling of endogenous catecholamines and vanillylmandelic acid (VMA). Determination of the changes in specific activity of these compounds with time in fractional collections of urine and in cardiac biopsies from patients undergoing corrective cardiac surgery permitted estimation o...

A continuous-flow method is described for achieving high-resolution separations with liquid-liquid partition without the use of an inert support. The instrument consists of a 60-rn coil of Teflon tubing (0.85 mm i.d.) mounted planetarily on a centrifuge arm. The coil is filled with the stationary phase and the mobile phase is pumped through the column in a direction opposing the flow of the sta...

Motivated by current trends in cloud computing, we study a version of the generalized assignment problem where a set of virtual processors has to be implemented by a set of identical processors. For literature consistency, we say that a set of virtual machines (VMs) is assigned to a set of physical machines (PMs). The optimization criteria is to minimize the power consumed by all the PMs. We te...

Noradrenaline (NA) levels in blood and urine were measured in 7 male adults before, during, and after a mild ergometer exercise. Blood pressure (BP) and heart rate (HR) were continuously recorded during all of their stages. Blood specimens were obtained with a catheter introduced into the antecubital vein and plasma NA (PNA) level was measured with high performance liquid chromatography (HPLC) ...

We describe a method for determining the "total" excretion of acidic metabolites of catecholamines by measuring 3,4-dihydroxyphenylacetic acid (DOPAC) formed by hydriodic acid hydrolysis of 4-hydroxy-3-methoxyphenylacetic acid (HVA), 4-hydroxy-3-methoxymandelic acid (VMA), and their conjugates. The DOPAC in the diluted hydrolysate is measured directly by liquid chromatography with electrochemic...