Acute retinal necrosis (ARN) is a clinical syndrome characterized by vitritis, severe occlusive vasculitis which produces a full thickness, necrotizing retinitis. The disease is caused by an acute infection with a member of the herpes virus family,usually VZV or HSV. ARN usually occurs in healthy adults; however immunocompromised patients may also be affected. The prognosis is poor, with signif...

OBJECTIVE To describe outcomes of and risk factors for endophthalmitis after intravitreal anti-vascular endothelial growth factor (VEGF) injection. DESIGN Single-center, consecutive, case series and retrospective case-control study. PARTICIPANTS Between January 1, 2009, and May 31, 2010, 16 vitreoretinal surgeons administered a total of 27 736 injections. During this period, 23 cases of pre...

Dear Editor: Acquired Toxoplasma gondii ocular infection usually presents with necrotizing retinochoroiditis with dense vitritis and vasculitis. Atypical disease has been observed in im-munocompromised states such as malignancy and AIDS 1 or after iatrogenic systemic 2 or local 3 immunosuppression. Intravitreal triamcinolone acetonide (TA) is used frequently by ophthalmologists for conditions l...

BACKGROUND While the development of targeted molecular therapy to inhibit vascular endothelial growth factor (VEGF) has revolutionized the treatment and visual prognosis of highly prevalent retinal diseases such as diabetic retinopathy and age-related macular degeneration, each intravitreal injection of these agents carries a small risk of endophthalmitis which can be visually devastating. In t...

BACKGROUND To report a case of masquerade syndrome presenting as bilateral uveitis in an HCV positive patient, and to highlight the difficulties in distinguishing between chronic uveitis and malignancy-induced inflammation. CASE REPORT In January 2005 a 54-year-old Caucasian man was referred to the Ophthalmological Department for bilateral visual loss, severe vitritis, and a significant catar...

PURPOSE To describe the incidence, timing, visual significance, and management of posterior segment complications after Boston type I keratoprosthesis implantation. METHODS A retrospective chart review was conducted of all consecutive Boston type I keratoprostheses implanted by a single surgeon at a single institution over a 6-year period. Preoperative demographics, postoperative complication...

PURPOSE To report the frequency and clinical features of sterile inflammation after intravitreal aflibercept injection in a Korean population. METHODS A single-center, retrospective study was performed in patients who received intravitreal aflibercept from July 2013 through January 2015. RESULTS A total of four cases of post-injection sterile inflammation were identified from 723 aflibercep...

The study aimed to describe the effectiveness of switching the anti-TNFα agent when an acceptable clinical response has not been obtained with the first anti-TNFα agent in patients with uveitis in VKH syndrome. Patients diagnosed with VKH syndrome being evaluated from the uveitis unit of a single tertiary hospital from January 1, 2000, to October 30, 2015. Patients who presented uveitis with an...