delivery of exogenous materials such as nucleic acids, peptides, proteins, and drugs into cells is an important strategy in modern cellular and molecular biology. recently, the development of gene carriers for efficient gene transfer into cells has attracted a great attention. furthermore, lack of effective drug delivery is one of the major problems of cancer chemotherapy. many physical methods...

context: detection of causative pathogen is crucial for treatment strategies in most infections. molecular diagnosis as a more sensitive and specific method, has become the best option to investigate certain pathogens, mainly viruses. recent scientific and technological approaches resulted in changing the area of diagnostic microbiology. evidence acquisition: a comprehensive online search of da...

to improve commercial grapevine cultivars, it is necessary to apply such methods that by cultivation of a certain number of vines in a certain area, higher yield could be harvested. to achieve such a goal, healthy stocks with resistant to pests and diseases, high fructification and high quality of vines are needed. all these properties can be obtained successfully through clonal selection. viti...

following experimental inoculation of 3-week-old turkeys with different titres (106, 104, 103, 102 and 101 egg infectious dose (eid50)) of a/ostrich/italy/984/2000 h7n1 highly pathogenic avian influenza virus (hpaiv), the selected tissues and organs were examined for pathological changes. tissue samples from different organs that obtained from dead and sacrificed birds were fixed in 10% neutral...

SRC kinases and PKR are intracellular protein kinases, which play key roles in intracellular viral replication. In this research, the effect of SRC kinase inhibition and PKR activation and inhibition on replication of coxsakievirus (CVB3), an entrovirus of the family picornaviridae – causative agents of fatal myocarditis, was studied. Vero and Hela cells were cultured and infected with CVB3 in ...

COVID-19 es una enfermedad viral que fue declarada pandemia por la Organización Mundial de Salud (OMS) durante el año 2020 ha causado un gran impacto en área médica, y específicamente radiología. El rol del radiólogo fundamental para identificar forma correcta las manifestaciones esta enfermedad, principalmente los hallazgos pulmonares imágenes. Sin embargo, último tiempo se han descri...

COVID-19 es una enfermedad infecciosa respiratoria aguda, causada por el SARS-CoV-2, un nuevo coronavirus, que se extendió rápidamente todo mundo, dando como resultado pandemia. Los pacientes presentan amplio espectro de manifestaciones clínicas, entre ellas, la miocarditis, y manera alterna, algunos sin síntomas cardíaca, tienen anomalías en las pruebas, elevación troponina arritmias cardíacas...