one hundred sera from children 1 - 6 years of age, representative of a large serum collection, were tested for the prevalence of antibodies against different viruses. hemagglutination-inhibition (hi) antibodies were found in 68% for measles; 61 % for rubella; 75'% for influenza a2/hong kong/68, 16% for influenza b/md./59, 0% for group a arboviruses, 10% for group b arboviruses, 3% for phlebotom...

viral myocarditis is a common cardiovascular disease, which has greatly threatened human health. however, up to now, the pathogenesis of viral myocarditis has been unclear, which leads to the lack of its effective treatments. to investigate the role of chemokines in pathogenesis of viral myocarditis, mrna expression for a panel of 19 chemokines detected by rt-pcr in myocardial tissue of balb/c ...

conclusions there is an as yet unexplained association between hcv and host parameters with unknown mechanisms in patients with chronic hcv infection. the assessments of core aa 70 substitution and polymorphisms near the ifnl3 gene could offer promising steps to improve the management of patients with hcv. background molecular studies have demonstrated that the hepatitis c virus (hcv) genotype ...

protease 2a (2apro) of coxsackievirus b3 (cvb3) plays a major role in viral replication. in case of infection, viral proteins are being synthesized from viral mrna using host biosynthesis machinery. 2apro of virus, after being synthesized, exhibits two critical functions, cleavage of viral proteins and breaking eukaryotic initiation factor 4g. the enzyme plays an essential role in viral replica...

there are many effective chemothereutic agents used in influenza disease which some of them inhibit virus replication by interfering with fluv (influenza virus) viral binding or its penetration into cell membrane. a series of polyoxometalates compounds such as pom-523 and pm-504 have been synthesized and have showed inhibitory effects on viruses. in this study we examined anti influenza activit...

conclusions given the non-specific symptoms of these viruses and the high prevalence of viral diarrhea in our region, more laboratories should be equipped for virus detection and vaccination might be considered as a prevention strategy. results rotavirus was identified in 347 patients out of 827 (42%), adenovirus was detected in 76 (9%) of samples and 34 (4%) of patients had rotavirus-adenoviru...

background viral meningitis is an inflammation of the leptomeninges as a manifestation of central nervous system (cns) infection. more than 85% of viral meningitis cases are caused by non-polio enteroviruses. this is the first study on the description of the enteroviruses and the related serotypes involved in viral meningitis in iran. objectives this project was conducted to improve our knowled...