Manuka honey (MH, 5g/kg) provided protection against trinitro-benzo-sulphonic acid induced colonic damage. Combination therapy (MH+sulfasalazine) also reduced colonic inflammation and all the biochemical parameters were significant compared to control and MH alone treated group. Combination therapy showed additive effect of the MH which restored lipid peroxidation and improvement of antioxidant...

This study has developed an innovative method for the production of secondary metabolites starting from Cydonia oblonga Mill (quince) pulp callus culture. The qualitative and quantitative content phenolic triterpenic acids quince extract were elucidated by GC–MS, GC, HPLC-DAD-ESI-MSn. was rich 5-O-caffeoylquinic acid (5-CQA), 5-p-coumaroylquinic (5-p-CoQA) maslinic corosolic acid. Quince extrac...

route to vinyl epoxides and vinyl aziridines via chiral sulfur ylides, we were keen to develop their potential in synthesis further. It had been reported that palladium-catalyzed reactions of vinyl epoxides and aziridines with doubly activated Michael acceptors gave tetrahydrofurans and pyrrolidines in good yield but usually with poor stereocontrol. However, related reactions with singly activa...

The application of enzymes in extraction processes within the food industry has not been widely explored. In this paper, an enzyme-assisted water method was employed and optimized to extract antioxidative phenolic compounds from pericarp Garcinia mangostana L. Fractional factorial design (FFD) developed screen out significant factors five parameters, including enzyme concentration, liquid-solid...

In order to understand antidiabetic potential and toxicity, this study aimed evaluate the acute toxicity activity of ethanolic extract ethyl acetate fraction obtained from Coutoubea spicata “nicolau” shoots. Chemical constituents were investigated. alloxan-induced diabetic rats, tested at dose 100 mg/kg, p.o. Body weight gain, glucose, lipid profile oxidative stress markers in serum tissues det...

The bioactive compounds and antioxidant activity of aronia leaves at different stages of maturity were identified and evaluated. Young and old leaves were approximately 2 months of age and 4 months of age, respectively. The young leaves contained more polyphenols and flavonoids than the old leaves. Three phenolic compounds (i.e., chlorogenic acid, p-coumaric acid, and rutin) were detected by HP...