Background Intracranial atherosclerosis related large vessel occlusion (ICAS‐LVO) is the major cause of failed mechanical thrombectomy. ICAS‐LVO causes reocclusion or a fixed focal stenosis, leading to suboptimal revascularization and poor functional outcomes. We aimed externally validate 4 preidentified imaging biomarkers ICAS‐LVO: absent hyperdense sign, Hounsfield units (Hu ratio ≤1.1 Delta ...

The ability of contrast echocardiography to assess regional myocardial perfusion during cardiopulmonary bypass in a dog model for coronary artery bypass surgery was evaluated. Sonicated Renograffin-76 microbubbles (meglumin diatrigoate and sodium diatrigoate) were injected into an aortic root proximal to an aortic occlusion clamp root while dogs were on cardiopulmonary bypass, with the heart ar...

A highly interconnected network of arterioles overlies mammalian cortex to route blood to the cortical mantle. Here we test if this angioarchitecture can ensure that the supply of blood is redistributed after vascular occlusion. We use rodent parietal cortex as a model system and image the flow of red blood cells in individual microvessels. Changes in flow are quantified in response to photothr...

With the recent advent of suction catheters, the use of manual aspiration thrombectomy (MAT) for patients with acute ischemic stroke with large vessel occlusion has increased. Although contrast leakage and subarachnoid hemorrhage have been reported during MAT procedures, pseudoaneurysm formation due to vessel injury by suction catheters has not been. We discuss the case of a 60-year-old woman w...

BACKGROUND AND PURPOSE Information on the clinical and hemodynamic profile of intravenous tissue-type plasminogen activator nonresponders, at different locations of arterial occlusion, may improve the selection of candidates for rescue reperfusion therapies. Therefore, we aim to investigate predictors of failing intravenous tissue-type plasminogen activator therapy according to occluded vessel ...

OBJECTIVE Twin-twin transfusion syndrome is a serious obstetric complication unique to monochorionic twin gestations. Occlusion of vessel anastomoses is recommended to improve the perinatal outcome. CASE REPORT A 36-year-old, gravida 1, woman had a monochorionic twin pregnancy which was found to be affected by twin-twin transfusion syndrome at 26 weeks' gestation. The condition was successful...

The pathogenesis of stroke Stroke is a heterogeneous condition in which 85% is caused by arterial acute occlusion or ischaemic stroke and 15% blood vessel rupture or cerebral haemorrhage. Of those with ischaemic stroke, further heterogeneity is evident with cerebral ischaemia caused by artery-to-artery emboli, in situ small vessel disease or cardiac emboli. The underlying pathogenesis can usual...

BACKGROUND Intimal hyperplasia of saphenous vein grafts (SVGs) can lead to subsequent graft atherosclerosis and occlusion after coronary artery bypass grafting (CABG). This study examined whether patient characteristics, anatomic factors, and medications are associated with SVG intimal hyperplasia and occlusion after CABG. METHODS AND RESULTS We performed a post hoc analysis of the Clopidogre...

conclusion coil embolization showed successful outcomes in the treatment of intracranial aneurysms with a low complication rate. results immediately after the procedure, the total occlusion was seen in 76 (86.4%), subtotal occlusion in six (6.8%), and partial occlusion in six patients (6.8%). there was no significant relationship between the aneurysm size, aneurysm neck size, and location of th...

&HEEL, KONRAD Mr., MANUEL BANET, COBERN OTT, AND PATRICK H. LEHAN. A quantitative approach to collateral and antegrade flows after coronary occlusion. Am. J. Physiol. 222(3): 687-694. 1972.-In an isolated dog heart preparation, the circumflex, anterior descending, and right coronary arteries were simultaneously perfused and blood flow was monitored by electromagnetic flow probes. The retrograde...