Transverse facial clefts (macrostomia) are rare disorders that result when the embryonic mandibular and maxillary processes of the first branchial arch fail to fuse due to failure of mesodermal migration and merging to obliterate the embryonic grooves between the maxillary and mandibular processes to form the angle of the mouth at its normal anatomic position. Macrostomia may be seen alone or i...

HESE studies were undertaken in order to repeat and supplement T the experiments of BEADLE and EPHRUSSI (1936,1937) and EPHRUSS~ and BEADLE (1936b) which provided the evidence upon which these authors postulated the existence of ca+ substance as one of three specific diffusible substances assumed to be necessary for the differentiation of wild type eye color in Drosophila melanogaster. The firs...

This paper reports an interesting development in a 64 year old female originally referred for evaluation of oral lichenoid lesions. The patient had a previous diagnosis of discoid lupus erythematosus of the skin. The presenting oral clinical appearance varied between lichenoid areas and ectopic erythema migrans. At initial presentation the patient had an exophytic lesion on the vermilion of the...

In continuation of the efforts made by the Illinois State Water Survey to develop a detailed hydrologic and water quality simulation model of the entire Illinois River Basin, a hydrologic simulation model was developed for the Vermilion River Watershed (one of the major tributaries of the Illinois River) to simulate streamflows using available climatic data. The model was developed using Hydrol...

A 13-year-old boy presents with asymptomatic lesions involving the mucosal aspects of his upper and lower lips. The lesions have been increasing in size and number over the past 5 months. He is not sexually active, is not taking any medications, and does not have a family history of a similar condition. Skin examination reveals multiple soft, mucosa-coloured papules, 2 to 8 mm in length, some w...

Exfoliative cheilitis, one of a spectrum of diseases that affect the vermilion border of the lips, is uncommon and has no known cause. However, factors such as stress and some psychiatric conditions are associated with the onset of the disease. This condition is disabling because esthetics and normal functions such as eating, speaking and smiling are compromised. The lack of specific treatment ...

We repaired a long horizontal defect in the lower lip caused by the resection of squamous cell carcinoma by reconstructing the white lip with a V-Y advancement flap and vermilion with a tongue flap. During this procedure, we deepithelialized the V-Y flap, lifted the upper margin of the flap and sutured it to the remaining upper margin of the lip, and then covered it with the tongue flap, result...