To the Editor: In the very interesting paper concerning takotsubo and long QT syndrome, published recently in the Journal,1 the authors concluded that many questions regarding the etiology, pathophysiology, and treatment of this syndrome remain unanswered and have asked for further studies in order to elucidate these issues. This follows previous appeals for worldwide efforts and research in or...

Stress-related cardiomyopathies can be observed in the four following situations: Takotsubo cardiomyopathy or apical ballooning syndrome; acute left ventricular dysfunction associated with subarachnoid hemorrhage; acute left ventricular dysfunction associated with pheochromocytoma and exogenous catecholamine administration; acute left ventricular dysfunction in the critically ill. Cardiac toxic...

Takotsubo cardiomyopathy occurs in patients with severe emotional or physiologic stress. The prognosis is usually favorable, and the left ventricular wall motion dyskinesis normalizes within days to weeks. In this paper we report a case of snake bite complicated by takotsubo cardiomyopathy. We advise physicians to consider not only cardioinhibitory effect of snake venom but also takotsubo cardi...

El Sindrome de Takotsubo es una disfuncion ventricular aguda reversible en ausencia obstruccion coronaria. Una mujer 85 anos edad con antecedentes reemplazo valvular aortico transcateter, ingreso por dos semanas dolor severo cadera desplazada osteosintesis fallida. Mientras se programaba para cirugia, documento hiponatremia severa secundaria a secrecion inapropiada hormona antidiuretica. Subita...

Takotsubo cardiomyopathy is an uncommon clinical entity, also called apical ballooning syndrome, characterized by transient systolic dysfunction of the apical and/or mid segments of the left ventricle. We report a case that highlights takotsubo syndrome in the setting of thyrotoxicosis that required thyroidectomy. The association of takotsubo syndrome and hyperthyroidism has been reported befor...

Objective Left ventricular outflow tract (LVOT) obstruction is a complication in 15-25% of patients with Takotsubo cardiomyopathy and sometimes leads to catastrophic outcomes, such as cardiogenic shock or cardiac rupture. However, the underlying mechanisms have not been clarified. Methods and Results We experienced 22 cases of Takotsubo cardiomyopathy during 3 years, and 4 of these 22 cases wer...

Choi et al. compared 20 patients with definite pheochromocytoma and various cardiac manifestations to 20 controls with Takotsubo after intense emotional stress. However, the usual diagnostic criterion for Takotsubo cardiomyopathy is self-improvement and (complete or near complete) correction of motion abnormalities. Did the patients have to demonstrate this correction to be included in the Tako...

We report five consecutive patients with transient midventricular dyskinesia, a recently described variant of transient apical dyskinesia. It is a syndrome that shares a broad clinical, prognostic and, probably, pathogenetic resemblance to the latter. The patients, the majority of whom were experiencing an episode of emotional or physical stress, were all admitted to an emergency department wit...

INTRODUCTION Takotsubo syndrome, also known as ampulla cardiomyopathy, broken heart syndrome, idiopathic apical ballooning syndrome, and stress-induced myocardial stunning, has been first described by Japanese authors in 1996 and subsequently specified in 2001; it derives from the resemblance between the ancient round-bottomed, narrow-necked Japanese fishing pots used to trap octopus in Asia an...