Why do newts survive after needle puncture of the heart despite significant hemorrhage into the thoracic cavity? The answer involves the unique anatomical changes in the circulation that occur after ventricular injury. If the ventricle ruptures, newts quickly develop valve hyperplasia at the location of both the ventricular inflow and outflow tracts so as to redirect blood flow away from the in...

BACKGROUND Thrombus aspiration (TA) has been shown to improve microvascular perfusion during primary percutaneous coronary intervention (PCI) for patients with ST-segment elevation myocardial infarction (STEMI). The objective of our study was to assess the relationship between TA and myocardial edema, myocardial hemorrhage, microvascular obstruction (MVO) and left ventricular remodeling in STEM...

Thrombin and iron are two major players in intracerebral hemorrhage-induced brain injury and our recent study found that thrombin contributes to hydrocephalus development in a rat model of intraventricular hemorrhage (IVH). This study investigated the role of red blood cell (RBC) lysis and iron in hydrocephalus after IVH. There were three parts to this study. First, male Sprague-Dawley rats rec...

BACKGROUND AND PURPOSE Both intraventricular fibrinolysis (IVF) and lumbar drainage (LD) may reduce the need for exchange of external ventricular drainage (EVD) and shunt surgery in patients with intracerebral hemorrhage and severe intraventricular hemorrhage. We investigated the feasibility and safety of IVF followed by early LD for the treatment of posthemorrhagic hydrocephalus. METHODS Thi...

A 53-year-old woman was referred because a CT scan disclosed a subarachnoid hemorrhage. An aneurysm was seen on digital subtraction angiography, which suddenly ruptured (video 1 on the Neurology® Web site at Neurology.org) during the study, suggesting the cause of the hemorrhage (video 2). The rate of contrast emission was 3 mL/s with a total volume of 16 mL; the pressure was 200 psi. External ...

Here, we present a case of dorsal medulla oblongata hemangioblastoma with fourth ventricular hemorrhage. A 23-year-old female developed sudden consciousness disturbance, and CT revealed hemorrhage in all cerebral ventricles and a hyperdense mass in the cisterna magna. Although the reddish tumor located in the dorsal medulla oblongata was successfully removed, she suffered from severe tako-tsubo...

Abstract Background Myxomas represent about 5–10% of primary cardiac tumors in children, and only 2.5–4% myxomas originate from ventricular chambers. Symptoms signs right depend mainly on the size site tumor its effect inflow outflow blood. Case presentation A 15-year-old female patient presented with syncope exertion symptoms congestive heart failure. She had a history dyspnea palpitation for ...

Introduction. External ventricular drain (EVD) placement is common among aneurysmal subarachnoid hemorrhage (aSAH). Draining cerebrospinal fluid (CSF) from the EVD also common, yet little known about how much to drain, length of time or drainage impacts patient outcomes.
 Aim. The purpose this study correlate amount CSF outcomes, via modified Rankin Score (mRS).
 Material and Methods....

The left ventricular assist device (LVAD) has been a standard of care for the management of patients with advanced heart failure since the 1990s. An increased risk of spontaneous bleeding related to the device has been noted, ranging from minor epistaxis to major thoracic and mediastinal hemorrhages. To our knowledge, intraocular hemorrhage has not been previously reported. We report a 72-year-...

We report the case of an eighteen year-old pregnant female with preeclampsia and florid signs and symptoms of posterior reversible encephalopathy syndrome (PRES) in whom intracerebral hemorrhage was evidenced following delivery. Management included blood pressure control, external ventricular drainage and lumboperitoneal shunt. To our knowledge this is the first report of intracranial hemorrhag...