Background: Adipokins are cytokines predominantely or exclusively expressed by adipose tissue that circulate and affect target tissues. Four known adipokines, adiponectin, visfatin/PBEF, omentin and vaspin, all increase tissue sensitivity to insulin, and are thus described as ’beneficial’. In this review such biological actions and potential roles of the adipokines leptin, adiponectin and resis...

Background: Vaspin is a novel anti-inflammatory adipokine associated with cardiovascular (CV) disease and inflammation in chronic inflammatory conditions different from axial spondyloarthritis (axSpA). 1 Given the high incidence of CV (mainly due to accelerated atherosclerosis) exhibited by axSpA patients, 2 we wondered if vaspin could also be key molecule this process. However, data on role re...

AMA Abdelhamed W, Morsy K, Hefny H, Abudeif A. The role of serum visfatin and vaspin in hepatocellular carcinoma hepatitis C-related liver cirrhosis. Clinical Experimental Hepatology - Manuscripts Accepted. 2023. doi:10.5114/ceh.2023.130499. APA Abdelhamed, W., Morsy, K., Hefny, H., & Abudeif, (2023). https://doi.org/10.5114/ceh.2023.130499 Chicago Walaa, Khairy H. Hesham M. Ahmed Abudeif. "The...

OBJECTIVE There is increasing evidence that adipocytokines may exert proinflammatory and destructive effects in rheumatoid arthritis (RA). Hence, the authors investigated the relationship between adipocytokines and several features associated with RA (inflammation, joint destruction and cardiovascular disease), as well as the effect of treatment with a tumour necrosis factor inhibitor or glucoc...

Chronic hepatitis C (CHC) is generally a slowly progressive disease, but some factors associated with rapid progression have been identified. Steatosis, independently of its metabolic or viral origin, leads to liver injury and fibrosis. It is suggested that hepatitis C virus may contribute to a wide spectrum of metabolic disturbances-namely, steatosis, insulin resistance, increased prevalence o...