Skeletal muscle contains multiple cell types that work together to maintain tissue homeostasis. Among these, satellite cells (SC) and fibroadipogenic progenitors (FAPs) are the two main stem pools. Studies of these using animal models have shown importance interactions between in repair healthy muscle, degeneration dystrophic muscle. Due unavailability fresh patient biopsies, similar analysis h...

This is a report of a penile fibrosarcoma in a two-year-old crossbred Holstein bull. The ulcerated tumormass with dimensions of 7 × 9 × 6.5 cm, was enveloped the glans and body of the penis. It had a white-graycolor at cross section appearance. There was no metastatic evidence of regional lymph node enlargement.Histopathologically, elongated spindle-shaped cells arranged densely in the interwov...

Previously considered passive support cells, mural cells—pericytes and vascular smooth muscle cells—have started to garner more attention in disease research, as subclassifications, based on morphology, gene expression, function, have been discovered. Central nervous system (CNS) arteriovenous malformations (AVMs) represent a neurovascular disorder which cells shown be affected, both animal mod...

microRNAs are a class of small RNAs that have been extensively studied, which involved in many biological processes and disease occurrence. The incidence intrauterine growth restriction is higher mammals, especially multiparous mammals. In this study, we found the weight longissimus dorsi growth-restricted pigs was significantly lower than normal pigs. Then, pig were used to characterize miRNA ...

a 75-year-old woman presented with six months history of progressing lagophthalmos and immobility of the left eye. magnetic resonance imaging (mri) of the orbit demonstrated infiltration of orbital fat and the extra-ocular muscles. we performed transverse blepharotomy of the left eyelid to correct lagophthalmos; and during surgery, we took a biopsy sample from levator muscle and orbital fat. af...

channelopathies are disturbances of the cellular membrane channels function. ion channels are actually membrane-bound proteins that perform key functions in virtually all human cells. these channels play pivotal role in the function of excitable tissues such as muscle and nerve. so channelopathies are diverse clinical entities involving many organs and systems (i.e., endocrine, respiratory, gas...

Many mammalian tissues have a specific cellular arrangement that enables their unique function. For example, parallel alignment of myofibers uniaxial muscle contraction. To engineer structured ex vivo, it is critical to recapitulate this arrangement. Conventional 3D encapsulation often fails complexity, motivating the need for advanced patterning approaches. In work, an acoustofluidic device co...