The present study was designed to examine the relationship between homocyst(e)ine (H[e]) levels and muscle mass. Two experimental groups each of 24 Caucasian males, one consisting of higher-muscle mass subjects (HMM) and the other of lower-muscle mass subjects (LMM) participated in this study. Muscle mass was estimated from 24-hour urine collections of creatinine (Crt). Muscle mass was 40.3 ± 1...

BACKGROUND There is relevant between individual variability in paracetamol clearance in young women. In this pooled study, we focused on the population pharmacokinetic profile of intravenous paracetamol metabolism and its covariates in young women. METHODS Population PK parameters using non-linear mixed effect modelling were estimated in a pooled dataset of plasma and urine PK studies in 69 y...

OBJECTIVES Our study examined: 1) racial/ethnic differences in sodium and potassium intake; and 2) racial/ethnic differences in the relationship between dietary intake and blood pressure. DESIGN & METHODS Data were collected in New York City in 2010, and included a telephone health survey, a 24-hour urine collection and an in-home clinical exam. Linear regression was used to examine the assoc...

Serial six hourly urine collections were made for seven days on 20 patients with acute pancreatitis. Quantitative immunoassay of urinary albumin and IgG on the first urine sample after admission showed increased excretion rates in 14 and 13 patients, respectively. Urinary protein excretion rates remained normal or approached normal by seven days in 17 patients who made uneventful recoveries. Th...

BACKGROUND Previous studies on dietary magnesium and risk of ischemic heart disease (IHD) have yielded inconsistent results, in part because of a lack of direct measures of actual magnesium uptake. Urinary excretion of magnesium, an indicator of dietary magnesium uptake, might provide more consistent results. OBJECTIVE The objective was to investigate whether urinary magnesium excretion and p...

The 1-hour serum xylose (surface area corrected) as an indication of xylose absorption after 5 g oral D-xylose has been compared with the 5-hour urine excretion test in a tropical population. The study confirmed that the peak serum xylose concentration occurs at 1 hour and that correction to a constant body surface are improves the discrimination between subjects with normal and impaired xylose...

Radioimmunoassay (RIA) and thin-layer chromatography (TLC) were compared for morphine detection in an actual narcotic clinic setting. A choice of urines from all those screened by TLC allowed a critical comparison as to actual use or non-use of narcotic drugs, rather than a sampling at random in which the question of possible false positives or negatives cannot be conclusively answered. Althoug...

TO THE EDITOR—The recent article by Leis et al, “Reducing antimicrobial therapy for asymptomatic bacteriuria among noncatheterized inpatients: a proof-of-concept study” [1], reveals a novel way to manage the problem of unnecessary urine collection. However, this laboratory-based solution proposed by Leis et al does not address the complex behaviors leading to the unnecessary urine collection. I...

PURPOSE To evaluate the utility of urine protein/creatinine ratio (uPCR) measurements among healthy parturients at term we performed a prospective cohort study at a community teaching hospital. METHODS Serial urine samples were collected. Ninety-three women contributed 284 urine samples. uPCRs were determined. Multiple imputation and paired sampled analysis was performed when appropriate. R...

OBJECTIVES To evaluate whether the gold standard of 24-h urinary albumin excretion in preeclamptic women could be substituted by a shorter collection period. METHODS From each woman, three spot, two 12-h, and one 24-h urine samples were collected. For each sample, urine albumin concentrations in milligram per liter were analyzed by the immunoturbidimetric method. The albumin concentrations in...