CONTEXT Thyroid hormone, requiring adequate maternal iodine intake, is critical for fetal neurodevelopment. Perchlorate decreases thyroidal iodine uptake by competitively inhibiting the sodium/iodide symporter. It is unclear whether environmental perchlorate exposure adversely affects thyroid function in pregnant women. Thiocyanate, derived from foods and cigarette smoke, is a less potent compe...

Background: Transient neonatal hyperthyrotropinemia (TNH) occurs frequently in areas of iodine deficiency and may affect intellectual function and psychomotor performance. Design: A historical cohort study of intellectual development, psychomotor performance, urine iodine and thyroid function tests, performed in 9 years children with documented TNH at birth and control group. Subjects: Eighte...

BACKGROUND Universal salt iodization (USI) was introduced in China in 1995, but whether the iodine status is optimal is questionable. This study was conducted to assess the iodine nutrition among Zhejiang population in coastal regions in China. METHODS A cross-sectional survey for iodine nutritional status was conducted with general population (n=10,350), including pregnant and lactating wome...

Objectives. To discuss the characteristics of the amount of urinary total antioxidants in tumor diseases and the possibility of utilizing the changing regulation of urinary antioxidants to diagnose tumor diseases. Method. Urine and serum specimens from 130 healthy people were used to investigate the variation of antioxidant capacity against age. Urine and serum specimens from 44 unselected pati...

Urinary Iodine excretion is a useful and important indicator of the iodine status of a population. This study attempts to determine the urinary iodine concentration of non-pregnant, pregnant and lactating women, resident in the National Capital District of Papua New Guinea, so as to evaluate their status of iodine nutrition. The study population was made up of 56 non-pregnant, 40 lactating and ...

Dehydration is a major risk for contrast media (CM) induced acute kidney injury, yet prospective studies in human patients without ample hydration are not feasible. The freely drinking rat can serve as a model for hydropenic humans. We compared the effects of two CM, iso-osmolar iodixanol and lowosmolar iopamidol, on urine flow, urine viscosity and glomerular filtration rate (GFR) in non-hydrat...

B A C K G R O U N D Th i s review is based on the report of the subcommittee for the study of endemic goiter and i od ine deficiency o f the European Thy ro i d Assoc iat ion (1,2). Ep idemio log i e Information on the prevalence o f goiter and al imentary iodine supply is scanty for most European countries. A l though regional data are avai lable, these do not necessarily reflect the Situation...

Adequate intake of iodine is essential for proper thyroid function. Although dietary reference intakes for iodine have been established, iodine intake cannot be estimated due to the lack of data on iodine contents in foods. We aimed to determine if food group intakes can predict iodine status assessed by urinary iodine concentration (UIC) from spot urine samples of 5967 US adults in the Nationa...

BACKGROUND Lack of knowledge about iodine may be a risk factor for iodine deficiency in pregnant and lactating women. The aim of this study was to assess knowledge about iodine and predictors of iodine knowledge scores among pregnant and lactating women. The study also examined whether iodine knowledge scores were associated with iodine status. METHODS A cross-sectional study was performed on...