Par many years it has been known that purine catabolism in the rat results in the formation and subsequent urinary excretion of allantoin as the main end-product. Individual enzymes catalyzing the steps in purine catabolism have been identified and methods for assaying these enzymes in vitro have been developed. With the discovery that xanthine oxidase activity in vitro is influenced greatly by...

BACKGROUND Advanced chronic kidney disease (CKD) is associated with the development of renal metabolic acidosis. Metabolic acidosis per se may represent a trigger for progression of CKD. Renal acidosis of CKD is characterized by low urinary ammonium excretion with preserved urinary acidification indicating a defect in renal ammoniagenesis, ammonia excretion or both. The underlying molecular mec...

Abstract Background Wilson’s disease is a multisystem disorder with predominant clinical symptoms depending on the site of copper deposition in body. Hepatic presentation usually seen younger age group. And pancreatitis rarely associated disease. To best our knowledge, recurrent acute as presenting manifestation WD patient has not been mentioned before literature. Case We report 17-year-old boy...

background klebsiella pneumoniae is a family member of enterobacteriaceae. isolates of k. pneumoniae produce enzymes that cause decomposition of third generation cephalosporins. these enzymes are known as extended-spectrum beta-lactamase (esbl). resistance of k. pneumoniae to beta-lactamase antibiotics is commonly mediated by beta-lactamase genes. objectives the aim of this study was to identif...

background: due to difficulty of obtaining a 24h urine (especially in children), a random urine calcium sample is recommended to detect of hypercalciuria. however, recent studies have shown that the urinary calcium/creatinine ratio varies with age and geographic areas. so, the aim of this study was determining the normal value of urinary calcium to creatinine ratio in healthy adolescent’s child...

serratia marcescens (s.m) is a species of gram–negative bacteria in the family enterobacteriaceae. a human pathogen, s. marcescens is involved in nosocomial infections, particularly in urinary tract and wound infections. this report describes a 63 years-old man that referred to hospital with dyspnea fc iv and he underwent cardiac valves replacement surgery with a diagnosis of severe mitral sten...

conclusions vur might be more frequent in children with physiological urinary incontinence than the normal population, and might be as common as nmne with intermittent daytime incontinence. results urinary tract infection was found in 23 (34.8%) children, 17 (33.3%) and 6 (40%) patients with nmne and physiological urinary incontinence, respectively. out of 48 patients who underwent vcug, vesico...

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Serratia marcescens is a Gram-negative rod intrinsically resistant to polymyxins and usually associated with wound, respiratory and urinary tract infections. The whole genome of the first GES-5-producing S. marcescens isolated from a Brazilian patient was sequenced using Ion Torrent PGM System. Besides blaGES-5, we were able to identify genes encoding for other β-lactamases, for aminoglycoside ...

cystoscopy and urinary cytology are currently the basis for diagnosis and ‎follow-up of bladder tumors. research to find a sensitive and specific tumor ‎marker for diagnosis of bladder tumor is actively underway, however, due to low sensitivity ‎and high cost of cytology. this cross-sectional study was performed in 65 patients to evaluate whether urinary bladder ‎cancer (ubc) antigen level can ...