background: impact of high level of uric acid on stroke is still controversial. we conducted this study to investigate the relationship between acute ischemic non-embolic stroke and serum levels of uric acid. methods: this was a case-control study on patients with acute ischemic non-embolic stroke in rafsanjan, iran. the control group consisted of normal persons who were similar to the case gro...

Objective: Urolithiasis remains a global problem. Despite the availability of numerous methods, no definite therapeutic agent has been yet introduced for the prevention or treatment of kidney stones. In this study, we evaluated the possible preventive effects of aqueous extract of Cichorium intybus L. (chicory) flowers on ethylene glycol-induced renal calculi in rats. Materials and Methods: A t...

BACKGROUND AND OBJECTIVES Sodium thiosulfate (STS) reduced calcium stone formation in both humans and genetic hypercalciuric stone forming (GHS) rats. We sought to measure urine chemistry changes resulting from STS administration in people. DESIGN SETTING PARTICIPANTS MEASUREMENTS: STS was given to healthy and hypercalciuric stone forming adults. Five normal non-stone forming adults (mean age 3...

background: the role of uric acid as a risk factor for vascular disease and acute stroke is controversial and there is little information about it. in this study, we determined serum uric acid levels in patients with acute stroke and assessed its relationship with cerebrovascular risk factors. methods: in this cross sectional study, we assessed patients with acute stroke who were admitted in fi...

OBJECTIVES Urolithiasis is a considerable economic burden for health systems, especially in industrialised countries where the incidence of stone disease has increased during the last few decades, and probably will further increase for several reasons. METHODS The survey was based on investigations in collaboration with a German health insurance company and on a literature search (PubMed, and...

The use of dual-energy computed tomography (DECT) for evaluating urinary calculi has been appreciated due to the modality's capability of differentiating between uric acid (UA) and non-UA stones, which are color coded based on a postprocessing algorithm. No other imaging modality or laboratory test is able to identify the stone composition without first attaining the stone material. Knowledge o...

The purpose of this literature study is to give an overview of nitrogen and purine metabolism in general and in particular of the molecular mechanisms for the higher uric acid excretion in Dalmatian dogs. The character portrayed by the Dalmatian breed appears to be connected whit a malfunction within purine metabolism, some studies point at a kidney disease whereas other at a liver disease. Alt...

BACKGROUND AND OBJECTIVES Medullary sponge kidney (MSK) is a renal malformation typically associated with nephrocalcinosis and recurrent calcium stones. Incomplete distal renal tubular acidosis, hypocitraturia, and hypercalciuria are common. For stone prevention, patients with MSK generally receive the standard "stone clinic" recommendations and often receive potassium citrate (KC). However, th...

background: dilated cardiomyopathy (dcmp) is a myocardial disease characterized by dilated left ventricle or both ventricles and reduced contractility of the myocardium. in patients suffering from dcmp, the serum level of uric acid may increase. this research was designed to evaluate the effect of the serum level of uric acid on systolic and diastolic functions in patients with dcmp. methods: t...