In rat pancreatic islets chronically exposed to high glucose or high free fatty acid (FFA) levels, glucoseinduced insulin release and mitochondrial glucose oxidation are impaired. These abnormalities are associated with high basal ATP levels but a decreased glucoseinduced ATP production ( of increment over baseline 0.7 0.5 or 0.5 0.3 pmol/islet in islets exposed to glucose or FFA vs. 12.0 0.6 i...

The relevance of elevated plasma levels of serum uric acid (SUA) in patients with cardiovascular disease was historically described 2 centuries century ago when Alexander Heig published a paper dealing with the causative role of hyperuricermia in patients with hypertension and several other diseases. More recently, a remarkable number of epidemiological and experimental studies have demonstrate...

In the ethics of relations between physicians and paediatric patients the question of autonomy and its corollary, consent, is crucial. While the importance attached to autonomy in the clinical setting is not the same as that accorded in research, it nonetheless assumes greater relevance when minors are involved, and a careful case-by-case assessment becomes obligatory. In a book published in 19...

s of the10th Meeting of the Italian Peripheral Nerve Study Group Verona, March 17–19, 2006 PHENOTYPICAL AND GENOTYPICAL HETEROGENEITY OF CHARCOT-MARIE-TOOTH DISEASE TYPE 2A ASSOCIATED WITH THE MITOFUSIN 2 GENE (MFN2) Angiari C, Cavallaro T, Ferrarini M, Taioli F, Cabrini I, Ferrari S, Fabrizi GM, Rizzuto N. Department of Neurological and Visual Sciences, Section of Clinical Neurology, Universit...

NEUROPSYCHIATRIC DEPARTMENTS IN THE PERSIAN HOSPITALS FROM ANCIENT TIMES TO 15 CENTURY Seyedeh Aida Ahmadi, Arman Zargaran Student Research Committee, Shiraz University of Medical Sciences, Iran ([email protected]), Research Office for the History of Persian Medicine, Shiraz University of Medical Sciences, Iran ([email protected]) The first hospital reported from 6 century AD was in the J...

The paper discusses the conventions used by medical practitioners to improve their collaboration mediated by Clinical Records. The case study focuses on the coordinative conventions identified in two wards of an Italian hospital and highlights their role and importance in the definition of the requirements of any system supportive of collaborative work practices. These requirements are expresse...

237P CMF-likeN % AnthracyclinesN % Anthra and TaxanesN % TaxanesN % Total Not Classified 9 14.8 26 42.6 23 37.7 3 4.9 61 ER+ HER2+ Ki67>19 4 3.7 57 53.3 43 40.2 3 2.8 107 ER+ HER2+ Ki67<20 3 5.8 22 42.3 27 51.9 0 0.0 52 ER+ HER2Ki67>19 26 9.7 131 48.7 101 37.5 11 4.1 269 ER+ HER2Ki67<20 29 10.1 137 47.9 106 37.1 14 4.9 286 ERHER2+ Ki67>19 4 4.9 44 53.7 33 40.2 1 1.2 82 ERHER2+ Ki67<20 0 0.0 10 ...