BACKGROUND There are no definitive markers to aid in diagnosis of neonatal encephalopathy (NE). The purpose of our study was (1) to identify and evaluate the utility of neuronal nitric oxide synthase (NOS1) in umbilical cord blood as a NE biomarker and (2) to identify the source of NOS1 in umbilical cord blood. METHODS This was a nested case-control study of neonates >35 weeks of gestation. E...

Background Fetal growth restriction is the second leading cause of perinatal morbidity and mortality. The incidence of intrauterine growth restriction (IUGR) is estimated to be approximately 5 percent in the general obstetric population. Abnormal uterine artery suggest a maternal cause for the growth restriction where as normal uterine artery Doppler studies suggest that a fetal cause. Use of u...

Umbilical hernias occur frequently in children but complications are rarely reported. This study assessed the incidence of complicated umbilical hernias in our patients, evaluated data for risk factors and reviewed our management in the light of these findings. We conducted a prospective study of all children needing umbilical hernia repair for complications over a period of 15 years. Patients ...

OBJECTIVE To determine the influence of presence of caffeine in umbilical cord blood on apnea occurrence. METHODS A prospective cohort study with preterm newborns with birth weight lower than 2,000 g was undertaken. Exclusion criteria were: mothers who received opioids; mechanical ventilation during the first 4 days of life; cerebral and major cardiac malformations; perinatal asphyxia; severe...

Umbilical endometriosis infrequently presents to the plastic surgeon. As such, the diagnosis is difficult to make because it is often overlooked. The current report presents a 35-year-old nulligravid woman with a six-month history of a firm, cyclically swelling lesion in her umbilical region. None of the signs characteristic of pelvic endometriosis except dysmenorrhea and a one-year history of ...

his umbilical hernia. The least degree of error consists in the persistence of a little pouch of umbilical ccelom in the thickness of the abdominal wall, which is later expanded into an ordinary skin-covered umbilical hernia. The greatest degree of error consists in the larger part of the abdominal viscera remaining in the umbilical cord. It is with this latter condition that we have to deal in...

A female patient presented with a painful swelling in the umbilicus. Ultrasonography demonstrated a hypodense nodule of 1.8 cm. Surgical exploration revealed a subcutaneous, dark discoloured, lobulated swelling at the bottom of the umbilicus, which turned out to be primary umbilical endometriosis (PUE). Primary umbilical endometriosis is a rare and benign disorder, caused by the presence of ect...