Although alternative splicing has been shown to give rise to isoforms of a number of transcription factors, such isoforms have not previously been detected for the POU homeodomain protein Pit-1. Screening of a rat pituitary GH3 cell cDNA expression library yielded a clone, termed pCMVPit-1a, encoding a 35.8 kD protein (Pit-1a) containing a 26 amino acid insert in the Pit-1 trans-activation doma...

Abstract. A limit analysis numerical procedure for the determination of a lower bound on ultimate load human proximal femur is presented. The procedure, already applied by authors in different contexts, based simplified 3D geometrical model and assumption few geometric material data available relevant literature. perfectly plastic behaviour bone, due to phenomena starting at molecular scale, or...