BACKGROUND Butyrate oxidation within the colonocyte is selectively inhibited by hydrogen sulphide, reproducing the metabolic lesion observed in active ulcerative colitis. AIMS To study generation of hydrogen sulphide by sulphate reducing bacteria (SRB) and the effects of 5-aminosalicylic acid (5-ASA) in patients with ulcerative colitis in order to identify a role of this noxious agent in path...

Cyclosporine may be considered as state of the art treatment for steroid resistant severe ulcerative colitis. Up to 30-40% of the patients with severe ulcerative colitis will fail to respond to intravenous steroid treatment and would require surgical treatment. I report a case of steroid resistant severe ulcerative colitis, which failed to respond to cyclosporine due to presence of cytomegalovi...

Fulminant ulcerative colitis is a potentially life-threatening disorder that requires expert management to allow for optimal outcomes. Once associated with very high mortality, 1 the medical and surgical treatment of fulminate ulcerative colitis has greatly improved such that mortality from fulminant ulcerative colitis currently is less than 3%. 2 , 3 Optimal management necessitates coordinatio...

strongyloidiasis disease caused by the strongyloidesstercoralis nematode .this disease mainly affects the intestines. sometimes the symptoms were similar to inflammatory bowel disease which may lead to misdiagnosis and lack of effective treatment. a 46-year-old male patient who complained of occasional diarrhea, sometimes with blood, about two months ago consulted with  an internist. he had col...

efficacy op cyclosporine in treatment of refractory ulcerative colitis

Patients of ulcerative colitis are mostly managed by physicians. Surgeons play a very pivotal role in curative treatment and in dealing with complications of ulcerative colitis. Various technical advances made in the field have reduced surgical morbidity and mortality in these patients with improvement in the quality of life. The article discusses the role of surgery and various surgical option...

A 9-year-old castrated male Chartreaux cat was presented for an ulcerative pododermatitis of all 4 paws. A clinical exam was inconclusive and supportive therapy did not improve the condition. Histologic examination revealed an ulcerative and eosinophilic dermatitis associated with epidermal and dermal nematodes and ova consistent with the aphasmid Anatrichosoma sp. Treatment with ivermectin com...

Skin Picking Disorder affects 4% of the general population, with serious quality of life impacts, and potentially life threatening complications. Standard psychoactive medications do not help most patients. Similarly, Mouse Ulcerative Dermatitis (skin lesions caused by excessive abnormal grooming behavior) is very common in widely used inbred strains of mice, and represents a serious animal wel...

background : many studies have investigated the effects of psychological factors on disease activity in patients with ulcerative colitis (uc). however, the number of studies that have assessed the correlation between immunologic markers of uc and psychological distress are few. therefore, we designed a study to determine the association between two immuno-biological markers, peripheral/central ...