Transcription factors play a central role in the epithelial-mesenchymal transition (EMT), which is one of the biomolecular mechanisms involved in the progression of urothelial carcinomas of the bladder (UCB). In this study, we analyzed the immunoexpression of Twist 1, Snail, Slug and β-catenin in relation to histopathological prognostic parameters of UCB. The obtained results indicated the asso...

BACKGROUND Sepsis and jaundice are common conditions in newborns that can lead to brain damage. Though lipopolysaccharide (LPS) is known to alter the integrity of the blood-brain barrier (BBB), little is known on the effects of unconjugated bilirubin (UCB) and even less on the joint effects of UCB and LPS on brain microvascular endothelial cells (BMEC). METHODOLOGY/PRINCIPAL FINDINGS Monolaye...

Brandon A. Jones(1), Alireza Doostan(2), and George Born(3) (1)(3)Colorado Center for Astrodynamics Research, University of Colorado Boulder, UCB 431, Boulder, Colorado, 80309, 303-735-4490, [email protected], [email protected] (2)Department of Aerospace Engineering Sciences, University of Colorado Boulder, UCB 429, Boulder, Colorado, 80309, 303-492-7572, alireza.doostan@colorad...

We describe the main technical difficulties in the proof for TS algorithm as compared to the UCB algorithm. In UCB algorithm, the suboptimal arm 2 will be played at time t, if its UCB value is higher, i.e. if UCB2,t−1 > UCB1,t−1. If we have pulled arm 2 for some amount of times Ω( log(T ) ∆2 ), then with a high probability this will not happen. This is because after n2,t ≥ Ω(log(T )/∆), using c...

Introduction: Squirting cucumber, Ecballium elaterium (L.) A. Rich. (Cucurbitaceae), is a wild medicinal plant found abundantly in the Mediterranean region. It has been utilized as a rootstock for many cucurbitaceous crops, mainly attributed to its resistance to abiotic as well as biotic stress (2). Important pharmacological uses (1, 9) are attributed to the bitter principles, cucurbitacins (5)...

In this paper an intelligent separation system, based on artificial neural networks (ANNs), for classifying four different varieties of Iranian pistachio nuts, namely, Kaleghouchi (Ka), Akbari (Ak), Badami (Ba) and Ahmadagaee (Ah) is presented. To develop the ANN models a total of 3200 pistachio sound signals, 800 samples for each variety, were recorded. Features of pistachio nut varieties were...

T he U.S. pistachio industry, which is located almost exclusively in Califor-nia, has experienced phenomenal growth over the past thirty years. The value of U.S. production of pistachios grew from nearly zero in 1976 to $333 million by 2002. The U.S. share of the rapidly growing global pistachio industry has also increased. Outside California, the main pistachio growing region is the Middle Eas...

doi: 10.1111/j.1399-3054.2006.00747.x Specific rootstocks can differentially influence the vegetative growth and development of fruit trees. However, the physiological mechanism involved in this phenomenon has been elusive. Recent research comparing different peach (Prunus persica L. Batsch) rootstocks suggests that the rootstock effect on vegetative growth in peach trees is associated to water...

Umbilical cord blood (UCB) has been used successfully as a source of hematopoietic stem cells (HSCs) for allogeneic transplantation in children and adults in the treatment of hematologic diseases. However, compared with marrow or mobilized peripheral blood stem cell grafts from adult donors, significant delays in the rates and kinetics of neutrophil and platelet engraftment are noted after UCB ...

Delayed hematopoietic recovery contributes to increased infection risk following umbilical cord blood (UCB) transplantation. In a Phase 1 study, adult recipients of UCB stem cells cultured ex vivo for 3 weeks with nicotinamide (NiCord) had earlier median neutrophil recovery compared with historical controls. To evaluate the impact of faster neutrophil recovery on clinically relevant early outco...