نتایج جستجو برای: type ii tgfβ receptor

تعداد نتایج: 2207007  

Journal: :Reviews in agricultural science 2022

In farm animals, both genetic and non-genetic factors affect reproductive traits. These can be categorized as intrinsic extrinsic. Extrinsic relate to the animal’s environment, while are related its genotype. Various traits studied concerning age, season, management, nutrition, body score, birth type. addition, variations of transforming growth factor-β (TGFβ) superfamily including BMPR-1B, BMP...

Journal: :Molecular cancer research : MCR 2015
Amanda L Balboni Pratima Cherukuri Matthew Ung Andrew J DeCastro Chao Cheng James DiRenzo

UNLABELLED The TGFβ superfamily regulates a broad range of cellular processes, including proliferation, cell-fate specification, differentiation, and migration. Molecular mechanisms underlying this high degree of pleiotropy and cell-type specificity are not well understood. The TGFβ family is composed of two branches: (i) TGFβs, activins, and nodals, which signal through SMAD2/3, and (ii) bone ...

2017
Heather A McCauley Véronique Chevrier Daniel Birnbaum Géraldine Guasch

Squamous cell carcinomas occurring at transition zones are highly malignant tumors with poor prognosis. The identity of the cell population and the signaling pathways involved in the progression of transition zone squamous cell carcinoma are poorly understood, hence representing limited options for targeted therapies. Here, we identify a highly tumorigenic cancer stem cell population in a mouse...

2015
Rajan Jain Christina E. Barkauskas Norifumi Takeda Emily J. Bowie Haig Aghajanian Qiaohong Wang Arun Padmanabhan Lauren J. Manderfield Mudit Gupta Deqiang Li Li Li Chinmay M. Trivedi Brigid L. M. Hogan Jonathan A. Epstein

The plasticity of differentiated cells in adult tissues undergoing repair is an area of intense research. Pulmonary alveolar type II cells produce surfactant and function as progenitors in the adult, demonstrating both self-renewal and differentiation into gas exchanging type I cells. In vivo, type I cells are thought to be terminally differentiated and their ability to give rise to alternate l...

پایان نامه :وزارت علوم، تحقیقات و فناوری - دانشگاه فردوسی مشهد - دانشکده مهندسی 1389

abstract type-ii fuzzy logic has shown its superiority over traditional fuzzy logic when dealing with uncertainty. type-ii fuzzy logic controllers are however newer and more promising approaches that have been recently applied to various fields due to their significant contribution especially when the noise (as an important instance of uncertainty) emerges. during the design of type- i fuz...

2006
Meihua Piao Osamu Tokunaga

To date, the glycoprotein endoglin and its receptor complex, formed between TGFβ and TGFβR-2, have been studied in tumor angiogenesis. The purpose of this study is to investigate the expression profile of endoglin and its receptor complex in human atherosclerotic lesions, and compare it to that in non-atherosclerotic tissues. Twenty-six atherosclerotic lesions and twenty-six non-atherosclerotic...

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