In terrestrial mammals, hearing starts with the perception of acoustic pressure by the tympanic membrane. Vibrations in this membrane are then transduced into the inner ear by the ossicle chain of the middle ear, composed of the malleus, incus and stapes. The proper connection of the ossicle chain with the tympanic membrane, provided by the insertion of the manubrium of the malleus into the ear...

The middle ear pressure variation is one of the most important factors that causes discomfort on flight passengers and crew. The purpose of this work is to develop a mathematical model of the middle ear cavity pressure variation during typical flight’s conditions. The middle ear cavity was modeled as a gas chamber that transfer gas to other physiological systems trough three different ways. One...

Methods: We conducted a retrospective chart review of all patients consecutively referred to the senior authors at a tertiary-care Pediatric Otolaryngology clinic for fi rst branchial cleft anomalies over a 14-year period. Patients underwent computerized tomography scan with contrast, otoscopy plus tympanic microsurgery, when indicated (29%), methylene blue mapping of the cutaneous opening, whe...

In order to elucidate the pathophysiology of an undetermined conductive deafness without perforation of the tympanic membrane, comparative study was made in several factor with conductive deafness which has normal tympanic membrane and may be due to inflammation. Differences and similarities in the manner of ossicular damage were discussed in these conductive deafness. The morbidity rate of con...

The standard treatment for acquired cholesteatoma involves surgical removal of the lesion and reconstruction of the tympanic membrane. In some children, these lesions can be treated more conservatively. We conducted a retrospective study of 29 ears in 24 children who had been treated for early acquired cholesteatoma with mechanical reduction and a tympanostomy tube. Outcomes measures included h...

OBJECTIVE To identify prognostic factors affecting outcome in lateral tympanoplasty for total or near-total tympanic membrane perforation. STUDY DESIGN Retrospective case series. METHODS Patients were those presenting with total or near-total tympanic membrane perforation undergoing lateral tympanoplasty from 1999 to 2004. We systematically collected demographic, clinical, audiologic, and o...

Objective: To report a novel case of Tarceva treatment for small cell lung carcinoma resulting in tympanic membrane necrosis. Patient: A 49-year-old male with tympanic membrane necrosis and presumed resistant acute otitis externa and chronic inflammation of the left ear. Patient is status post chemotherapy and radiation diagnosed with non-small cell lung cancer in December 2008 with on-going th...

OBJECTIVES Tympanic membrane perforations are common, but there have been few studies of the factors determining the extent of the resulting conductive hearing loss. The aims of this study were to determine whether the size of tympanic membrane perforation, pneumatization of middle ear & mastoid cavity, and location of perforation were correlated with air-bone gap (ABG) of patients. METHODS F...

The effect of the presence of tympanosclerotic plaques in tympanic membrane on the outcome of a myringoplasty procedure was evaluated in this retrospective study. Long-term results of 714 myringoplasties were analyzed, and of these, 555 were eligible for further study. Three groups were studied separately: ears without tympanosclerosis, ears with a plaque not exceeding one third of the tympanic...

INTRODUCTION Tympanoplasty is a standard procedure to repair tympanic membrane perforation. The aim of this study is to evaluate the results of tympanoplasty (hearing improvement and tympanic membrane closure rate) in patients suffering from chronic perforation of the tympanic membrane by considering the prognostic factors. MATERIALS AND METHODS In a prospective study, based on the results of...