Bacterial two-component signal transduction systems (TCSs) play a pivotal role in environmental adaptation. In this minireview, two TCSs in Escherichia coli are clarified: the PhoP/PhoQ system, which senses extracellular Mg and controls the expression of the genes for adaptation to environmental Mg deprivation (Mg regulon); and EvgA/EvgS, a signal transduction system that activates expression o...
