The hyperlipidemia accompanying infection has been attributed to production of tumor necrosis factor. This cytokine inhibits adipose tissue lipoprotein lipase, which could decrease clearance of lipoproteins. Infections also increase hepatic lipogenesis. We now have demonstrated that tumor necrosis factor-alpha stimulates lipid synthesis in vivo. 2 h after administration of tumor necrosis factor...

Presenter: Diamantis Tsilimigras MD | The Ohio State University Background: Tumor necrosis has been associated with unfavorable prognosis among patients hepatocellular carcinoma and hilar cholangiocarcinoma. prognostic impact of tumor undergoing resection for intrahepatic cholangiocarcinoma (ICC) remains ill-defined. Methods: Patients who underwent curative-intent ICC between 2000-2017 were ide...