PURPOSE In order to maximise the utility of [(11)C]-PBR28 for use in longitudinal studies and clinical trials in Alzheimer's disease (AD), there is a need to develop non-invasive metrics of tracer binding that do not require arterial cannulation. Recent work has suggested that standardised uptake value (SUV)-based methods may be sensitive to changes in translocator protein (TSPO) levels associa...

Thioredoxin reductase (TRR1) is an important component of the thioredoxin oxidative stress resistance pathway. Here we show that it is induced during oxidative and nitrosative stress and is preferentially localized to the mitochondria in Cryptococcus neoformans. The C. neoformans TRR1 gene encodes the low-molecular-weight isoform of the thioredoxin reductase enzyme, which shares little homology...

It had been thought that it is difficult to provide receiptfreeness in mixnet-based electronic voting schemes. Any kind of user chosen randomness can be used to construct a receipt, since a user can prove to a buyer how he had encrypted the ballot. In this paper we propose a simple and efficient method to incorporate receipt-freeness in mixnetbased electronic voting schemes by using the well kn...

New materials allow new building designs and construction types. However, initial projects using the show that traditional principles - in case of carbon reinforced concrete those derived from steel are still being used. In other words, conventional merely substituted. Only combined with intelligent strategies it is possible to exploit full potential innovative materials. Detached established p...

Our studies in yeast show that there is an essential requirement for either an active thioredoxin or an active glutathione (GSH)-glutaredoxin system for cell viability. Glutathione reductase (Glr1) and thioredoxin reductase (Trr1) are key regulatory enzymes that determine the redox state of the GSH-glutaredoxin and thioredoxin systems, respectively. Here we show that Trr1 is required during nor...

We study the gravitational corrections to the F-term in four-dimensional N = 1 U(N) gauge theories with flavors, using the Dijkgraaf-Vafa theory. We derive a compact formula for the annulus contribution in terms of the prime form on the matrix model curve. Remarkably, the full TrR ∧ R correction can be reproduced as a special momentum sector of a single c = 1 CFT correlator, which closely resem...