نتایج جستجو برای: triclabendazole proteome

تعداد نتایج: 17375  

2011
Allison Koester Russell Lundholm Mark Soliman Shiva Rajgopal Devin Shanthikumar

Why do large positive earnings surprises occur? The literature often treats large earnings surprises as the exogenous event that precipitates subsequent stock price drift, but analyst expectations and earnings realizations are the result of conscious decisions made by analysts and managers. While neither analysts nor managers have an obvious incentive for an extreme deviation between expected a...

2016
Quan Zhong Samuel J Pevzner Tong Hao Yang Wang Roberto Mosca Jörg Menche Mikko Taipale Murat Taşan Changyu Fan Xinping Yang Patrick Haley Ryan R Murray Flora Mer Fana Gebreab Stanley Tam Andrew MacWilliams Amélie Dricot Patrick Reichert Balaji Santhanam Lila Ghamsari Michael A Calderwood Thomas Rolland Benoit Charloteaux Susan Lindquist Albert-László Barabási David E Hill Patrick Aloy Michael E Cusick Yu Xia Frederick P Roth Marc Vidal

In cellular systems, biophysical interactions between macromolecules underlie a complex web of functional interactions. How biophysical and functional networks are coordinated, whether all biophysical interactions correspond to functional interactions, and how such biophysical-versus-functional network coordination is shaped by evolutionary forces are all largely unanswered questions. Here, we ...

2015
David Enard Le Cai Carina Gwennap Dmitri A. Petrov

Viruses interact with hundreds to thousands of proteins in mammals, yet adaptation 6 against viruses has only been studied in a few proteins specialized in antiviral defense. 7 Whether adaptation to viruses typically involves only specialized antiviral proteins or 8 affects a broad array of proteins is unknown. Here, we analyze adaptation in ~1,300 9 virus-interacting proteins manually curated ...

Journal: :Current opinion in chemical biology 2009
Mario Niepel Sabrina L Spencer Peter K Sorger

Recent advances in single-cell assays have focused attention on the fact that even members of a genetically identical group of cells or organisms in identical environments can exhibit variability in drug sensitivity, cellular response, and phenotype. Underlying much of this variability is stochasticity in gene expression, which can produce unique proteomes even in genetically identical cells. H...

Journal: :Proteomics 2006
Gilbert S Omenn Young-Ki Paik David Speicher

The Human Proteome Organization has several major collaborative research initiatives, including the Plasma Proteome Project. A major feature of the HUPO World Congress in Munich in August 2005 was the release of the special issue of PROTEOMICS with 28 articles from the pilot phase of the Plasma Proteome Project. An open Workshop and a presentation in the closing plenary session of the congress ...

Journal: :CoRR 2014
Jesse G. Meyer

In the post-genome era, biologists have sought to measure the complete complement of proteins, termed proteomics. Currently, the most effective method to measure the proteome is with shotgun, or bottom-up, proteomics, in which the proteome is digested into peptides that are identified followed by protein inference. Despite continuous improvements to all steps of the shotgun proteomics workflow,...

Journal: :Data in Brief 2021

Streptococcus equi subspecies ( S. ) is an opportunistic pathogen and a major causative agent of equine strangles, contagious respiratory infection in horses other equines. In this study, we provide the dataset associated with our research publication “ -derived extracellular vesicles as vaccine candidate against infections” [1]. We describe genomic differences between 4047 ATCC 39506 outline c...

Journal: :Biochemical Society transactions 2012
Natalia Sanchez de Groot Marc Torrent Anna Villar-Piqué Benjamin Lang Salvador Ventura Jörg Gsponer M Madan Babu

Protein aggregation is being found to be associated with an increasing number of human diseases. Aggregation can lead to a loss of function (lack of active protein) or to a toxic gain of function (cytotoxicity associated with protein aggregates). Although potentially harmful, protein sequences predisposed to aggregation seem to be ubiquitous in all kingdoms of life, which suggests an evolutiona...

2012
Annemarie J.S. Winkelhagen Theo Mank Peter J. de Vries Robin Soetekouw

1. European Food Safety Authority. EFSA Panel on Animal Health and Welfare; scientifi c opinion on African swine fever. EFSA Journal. 2010;8:1556. http://dx.doi. org/10.2903/j.efsa.20101556 2. Sanchez-Botija C. Reservoirs of ASFV: a study of the ASFV in arthropods by means of the haemadsorption test. Bull Off Int Epizoot. 1963;60:895–9. 3. Boinas FS, Wilson AJ, Hutchings GH, Martins C, Dixon LJ...

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