Trematodes cause disease in millions of people worldwide, but the absence commercial vaccines has led to an over-reliance on a handful monotherapies control infections. Since drug-resistant fluke populations are emerging, deeper understanding parasite biology and host interactions is required identify new drug targets immunogenic vaccine candidates. Mass spectrometry-based proteomics represents...

Neuroschistosomiasis (NS) is the second most common form of presentation of infection by the trematode, Schistosoma mansoni. Granulomatous inflammatory reaction occurs as a result of schistosome eggs being transmitted to spinal cord or brain via the vascular system, or by inadvertent adult worm migration to these organs. The two main clinical syndromes are spinal cord neuroschistosomiasis (acut...

The risk of exposure to Fasciola hepatica in horses from Uruguay was evaluated using ELISA and a recombinant surface protein (FhrAPS). Blood samples were collected from 368 horses from different districts. Detection of antibodies and the seasonal IgG pattern against the trematode was also established. The overall seroprevalence was 54% (ranging 23% November to 93% December). Significantly highe...

In order to determine potential definitive hosts of the digenetic trematode, Bolbophorus damnificus, two American White Pelicans (Pelecanus erythrorhynchos), two Double-crested Cormorants (Phalacrocorax auritus), two Great Blue Herons (Ardea herodias), and two Great Egrets (Ardea alba) were captured, treated with praziquantel, and fed channel catfish (Ictalurus punctatus) infected with B. damni...

this study conducted to provide the status of parasite communities of four sturgeon species viz. acipenser stellatus , a. gueldenstaedtii , a. nudiventris , and huso huso in the southwest of the caspian sea and their histopathological effects on the examined fishes. for this purpose a total of 93 individuals of four sturgeon species were caught in two fisheries regions from the southwest of the...