Abstract Background Reduction of the aortic valve area (AVA) may lead to stenosis with considerable impact on morbidity and mortality if not identified treated. Lipoprotein (a) [Lp(a)] also inflammatory biomarkers, including platelet derived have been considered risk factor for stenosis; however, association between Lp(a), biomarkers AVA among patients familial hypercholesterolemia (FH) is clea...

Abstract Background and Aims Secondary hyperparathyroidism (sHPT) is common in kidney transplant recipients. It remains unknown if Calcimimetic agents (as cinacalcet), oftenly used this context, have an impact on mortality or morbidity. The objective of work was to compare the renal cardiovascular outcome transplanted patients with sHPT. Method Data from January 2008 December 2019 were retrospe...

Antiangiogenic therapy attenuates tumor growth by reducing vascularization. Diazepam (DZP) and midazolam (MZL) have antiangiogenic properties in human umbilical vein endothelial cells. Thus, we investigated the antiangiogenic activity of DZP and MZL in the rat 9L gliosarcoma brain tumor model. The effect on tumor vasculature was evaluated using dynamic susceptibility contrast magnetic resonance...

the aim of this study was to evaluate the immune system and lymphocyte function in 41 iranian β-thalassemic patients and 50 controls, ages ranging from 2 to 18 years. the patients consisted of 20 splenectomized and 21 non-splenectomized patients. they were treated with desferal, and had received repeated blood transfusion. laboratory investigations included measurement of total t lymphocytes, a...

background chronic hypoxia causes apoptosis of cardiac myocytes, however, energy production by anaerobic glycolysis protects myocardium against hypoxia injuries. aldolase a is a well-characterised key enzyme of the glycolysis pathway. ghrelin, a 28-amino-acid peptide, synthesizes in the stomach and has protective roles in cardiovascular systems and also affects metabolic pathways. objectives th...

Abstract Background Treatment with thiopurines may be associated different adverse effects, including acute pancreatitis. Risk factors for developing pancreatitis due to in patients Inflammatory Bowel Disease (IBD) are not clearly identified, underlying genetic predisposition being a possible cause. Our aim was evaluate predictive pharmacogenetic risk of IBD treated thiopurines. Methods were id...

In organic farming, microwave irradiation can be used as an alternative to standard chemical seed treatment. The increase in temperature during this treatment may negatively affect the germination of low-quality seeds. aim study was evaluate effect microwaves on and health zinnia seeds using four samples varying initial quality. Seeds were placed a beaker with distilled water irradiated at powe...

background and objectives this study was undertaken to evaluate the effect of the cultivated satureja khuzestanica essential oil (skeo) on activity and gene expression of hepatic gk in normal and diabetic rats.   methods biochemical parameters such as glucose, insulin, and hba1c plasma levels and oral glucose tolerance test were all analyzed. the cultivated skeo was orally administered at diffe...