Epidermal growth factor receptor (EGFR) plays a critical role in mediating ultraviolet (UV) irradiation-induced signal transduction and gene expression in human keratinocytes. EGFR activation results from increased phosphorylation on specific tyrosine residues in the C-terminal intracellular domain. It has recently been reported that following growth factor stimulation EGFR translocates from th...

Molybdenum (Mo), boron (B), and iron (Fe) play an important role in symbiotic nitrogen fixation by legume plants. The intensity of this process varies different growth stages legumes, the changes are accompanied content translocation these micronutrients plant. A two-year field experiment was conducted to investigate dynamics molybdenum, boron, content, translocation, accumulation pea Two culti...

Urban soil pollution has become a major concern in megacities around the world. Due to their non-degradable characteristic, toxic metals are among the most notorious pollutants. In this study determination of total and bioavailable fraction of toxic metals Ni, Cu, Cr, Zn, Co, Cd, Pb and Mn, in surface soils of district 16th in Tehran municipality is considered. Furthermore, metals uptake potent...

The pleckstrin homology (PH) domains of a number of proteins have been found to interact in vitro with inositol phospholipids; recent experiments show that these interactions may be important in directing protein translocation to specific parts of the cell following stimulus-induced lipid breakdown or synthesis.

This experiment was carried out to study the effect of humic acid and growth promoting bacteria on uptake of cadmium heavy metal by annual alfalfa (Medicago scutellata L.). The experiment was arranged in pot experiment conditions in Isfahan, Iran in 2011. A factorial design was used based on completely randomized block design with four replications. Experimental treatments were humic acid and g...

In cells, helicase translocation along nucleic acid is essential for many biological processes. However, so far, the mechanism of this translocation is not fully understood. Recent studies show that helicase might translocate through two processes, active process and passive process, with different translocation rate. In this study, a mechanochemical model including such two processes is presen...

We investigate single-molecule electrophoretic translocation of A(50), C(50), A(25)C(50), and C(50)A(25) RNA molecules through the alpha-hemolysin transmembrane protein pore. We observe pronounced bilevel current blockages during translocation of A(25)C(50) and C(50)A(25) molecules. The two current levels observed during these bilevel blockages are very similar to the characteristic current lev...

uniparental disomy (upd) is a situation in which both members of a chromosome pair are inherited from one parent. this study has been conducted on a family with a five year-old healthy girl and a mentally retarded boy. the parents were first cousins and they both had robertsonian translocation between their long arm of chromosome 13 and 14 [45, xy t (13q14q)]. their affected son had a similar k...

a large number of simple or complex translocation involving the cml and aml chromosomal abnormalities has been described. this study was aimed to investigate the complex chromosome aberrations in the series of myeloid malignancies including cml and aml. the present report deals analyzed 187 consecutive with cml and aml patients, using methotrexate  cell synchronization and  un-stimulated cultur...

background: carriers of translocations may have an increased risk of an unbalanced progeny due to imbalances and delays in meiosis. case: a 24-year-old pregnant iranian female was referred to the genetic department of yazd clinical and research centre for infertility because of her pregnancy history. she had three previous pregnancies, two of which ended in abortion. the one live born infant wa...