ABSTRACT The classical neurotransmitter serotonin or 5-hydroxytryptamine (5-HT), synthesized from tryptophan, can be produced both centrally and peripherally. Through binding to functionally distinct receptors, is profoundly implicated in a number of fundamental physiological processes pathogenic conditions. Recently, has been found covalently incorporated into proteins, newly identified post-t...

Transglutaminases catalyze the posttranslational modification of proteins by transamidation of available glutamine residues. This action results primarily in the formation of epsilon-(gamma-glutamyl)lysine cross-links but includes the incorporation of polyamines into suitable protein substrates as well. The covalent isopeptide crosslink is stable and resistant to proteolysis, thereby increasing...

pH adjustment would be of advantage in improving the water holding capacity of muscle proteins. The objective of this study was to evaluate the addition of fish sarcoplasmic protein (SP) solution, which was adjusted to pH 3.0 or 12.0, neutralized to pH 7.0, and lyophilized to obtain the acid- and alkaline-treated SP samples, on the functional properties of the chicken myofibrillar protein induc...

In the current issue of Clinical Gastroenterology and Hepatology, Aronsson et al from The Environmental Determinants of Diabetes in the Young (TEDDY) study group explore the relationship between gluten intake and risk of celiac disease (CD) in genetically atrisk children. Although the data in this nested casecontrol study originated from Sweden where the rate of CD is highest, the TEDDY study g...