The main question addressed in this preliminary study is what traces of L1 have been transferred to L2 use. The focus is on the durational aspects of the tense-lax and quantity contrasts in English and Japanese. The results could be interpreted as support for the hypothesis that an L1 durational pattern rather than a specific phonetic feature is the object of transfer.

OBJECTIVES Naked DNA vaccines can be manufactured simply and are stable at ambient temperature, but require improved delivery technologies to boost immunogenicity. Here we explore in vivo electroporation for multivalent codon-optimized human papillomavirus (HPV) L1 and L2 DNA vaccination. METHODS Balb/c mice were vaccinated three times at two week intervals with a fusion protein comprising L2...

since the beginning of the presence of the holy qur’an, criticism and rhetoric have received attention in the areas of culture and thought, too. in this respect we can name some literary and rhetorical works like maj?z al-qur’?n by abu ubaydah ma’mar ibn muthann?, ket?b al-fas?hah by abu h?tam sajest?ni, e’j?z al-qur’?n by j?hez basri, naqd al-nathr wa naqd al-she’r by abu al-faraj qud?mah ibn ...

Based on observations of the rhythmic structure of L2-speech produced by L1-speakers of Albanian – which suggest the occurrence of transfer – a study is presented here that compares durational aspects between the two languages. In order to do this, speech read by Swedish and Albanian L1-speakers was recorded and investigated, and normalized durational factors were analysed. The results, however...

Exogenous transfer RNAs (tRNAs) favor translation of bovine papillomavirus 1 wild-type (wt) L1 mRNA in in vitro translation systems (Zhou et al. 1999, J. Virol., 73, 4972-4982). We, therefore, investigated whether papillomavirus (PV) wt L1 protein expression could be enhanced in eukaryotic cells following exogenous tRNA supplementation. Both Chinese hamster ovary (CHO) and Cos1 cells, transfect...

Increased remissions in multiple sclerosis (MS) during late pregnancy may result from high levels of sex steroids such as estrogen and estriol. Estrogen (E2=17β-estradiol) protects against experimental autoimmune encephalomyelitis (EAE), but the cellular basis for E2-induced protection remains unclear. Treatment with relatively low doses of E2 can protect against clinical and histological signs...

Most studies on bilingual language development focus on children's second language (L2). Here, we investigated first language (L1) development of Polish-English early migrant bilinguals in four domains: vocabulary, grammar, phonological processing, and discourse. We first compared Polish language skills between bilinguals and their Polish non-migrant monolingual peers, and then investigated the...

The growth of neuronal processes depends critically on the function of adhesion proteins that link extracellular ligands to the cytoskeleton. The neuronal adhesion protein L1-CAM serves as a receptor for nerve growth-promoting proteins, a process that is inhibited by the interaction between L1-CAM and the cytoskeleton adaptor ankyrin. Using a novel reporter based on intramolecular bioluminescen...