This issue of Breast Disease focuses on the subject of signal transduction and its role in the pathogenesis and progression of human breast cancer. Within the past 10 years, the explosion in our knowledge of these processes has significantly altered our understanding of breast cancer, and resulted in the first receptor-based therapies. This issue examines a variety of relevant signaling pathway...

130 INTRODUCTION Genetic transduction is the transfer, from one cell to another, of nonviral genetic material within a viral coat. Transduction was discovered by Zinder and Lederberg in 1952 (217, 218) during a search for genetic recombination in salmonellae. Expecting to find conjugative transfer, they grew two mutant strains together. Recombinants were indeed produced, but to the authors' sur...

The interaction between magnetic and acoustic excitations has recently inspired many interdisciplinary studies ranging from fundamental physics to circuit implementation. Specifically, the exploration of their coherent interconversion enabled via magnetoelastic coupling opens a new playground combining straintronics spintronics provides unique platform for building up on-chip information proces...

Protein arginine methylation is a widespread post-translational modification (PTM) in eukaryotic cells. This chemical proteins functionally modulates diverse cellular processes from signal transduction, gene expression, DNA damage repair,...

An opto-electronic switching device made from an evaporated spin crossover thin film over a graphene sensor is presented. The electrical transduction of both temperature and light-induced reversible transitions are demonstrated.

Piezoelectric optomechanical platforms represent one of the most promising routes towards achieving quantum transduction photons between microwave and optical frequency domains. However, there are significant challenges to near-unity efficiency. We discuss such factors in context two main approaches being pursued for high efficiency transduction. The first approach uses one-dimensional nanobeam...

Heme proteins take part in a number of fundamental biological processes, including oxygen transport and storage, electron transfer, catalysis signal transduction. The redox chemistry the heme iron biochemical diversity have led to development plethora biotechnological applications. This work focuses on biosensing devices based proteins, which they are electronically coupled an electrode their a...

The accumulation of abscisic acid (ABA) is considered a crucial signal for the onset berry maturation in grape berry, including ‘Kyoho’ (Vitis labruscana L.). Therefore, delay maturation, especially peel coloration, by applying an ABA inhibitor (nordihydroguaiaretic acid, NDGA) to clusters has been investigated various studies. Herein, we report first time that NDGA treatment on leaves inhibite...

Soil salinization poses a huge challenge to the development of agriculture and seriously decreases crop yield quality. In recent years, grafting has become one key agronomic techniques used enhance plant abiotic stress tolerance. this study, we found that watermelon [Citrullus lanatus (Thunb.) Matsum. & Nakai] grafted onto bottle gourd (Lagenaria siceraria Standl.) significantly enhanced sa...