background and objectives:  squill [drimia maritima (l.) stearn] is an important medicinal plant that has been used for medicinal purposes such as cardiovascular diseases and asthma since ancient times. bufadienolides are the main compounds of this plant and are responsible for some reported adverse effects. in order to reduce adverse effects, different methods like boiling with vinegar were ap...

the present study has been conducted on caspian roach (rutilus rutilus) so that the impact of different concentrations lead on blood hematological, biochemical, and immunological indicators could be investigated. the roach (rutilus rutilus), used in this study, was 3.3±0.3 g heavy and 4±0.80 cm long in average. the fish were exposed to a low concentration of 10% lc50 and high concentration of 5...

background and aims: quantum dots (qds), as colloidal nanocrystalline semiconductors, present qd wavelengths in terms of biomedical assays and imaging, though the high toxicity of their core demands to be taken into consideration. investigating this subject is taken into account as an important concept   concerning use of these nanoparticles in the medical applications. materials and methods: 1...

the aim of this investigation was to design and develop nanoemulsions as novel delivery systems for rapamycin. phase behavior of quaternary systems composed of traicetin (as oil), various surfactants and co-surfactants and water at different surfactant/co-surfactant weight ratios were investigated by the construction of phase diagrams. formulations were taken from the o/w ne region of the phase...

objective(s): the increasing use of methamphetamine (meth) in the last decades has made it the second most abused drug. advancs in the area of intravenous lipid emulsion (ile) have led to its potential application in the treatment of poisoning. the present study aims to investigate the potential role of ile as an antidote for acute meth poisoning. materials and methods: two groups of six male r...

background:every day, people with addiction cause heavy economic and cultural damage to society. in some circumstances, opioids are used as a tool for suicide, which is often seen in youth. the aim of this study was to investigate the clinical signs of toxicity associated with opium in patients referred to ardabil city hospital. methods:this is a cross-sectional study that has been done on opiu...

objective(s): nanomaterials, especially silver nanoparticles (ag-nps), are employed in an increasing number of commercial products. this has led to an ever growing exposure of human beings to this substance. the first purpose of the nano committee of food and drug administration of the islamic republic of iran (ifda) is developing guidelines to assess and approve commercial nano-health products...

abstract   background: lead toxicity is caused by ingestion, inhalation, or contact with particles or vapors containing lead. it can present with nonspecific signs and symptoms such as abdominal pain, constipation, irritability, difficulty concentrating, and anemia. in this study, we have tried to find a relationship between lead poisoning and drug abuse.   methods: in a cross sectional study, ...

background: glybenclamide and metformin are two of the most common oral hypoglycemic drugs which are often used in treatment of type ii diabetes mellitus. toxicity due to these drugs may occur intentionally, accidentally, or even at the normal dosage because of the progression of such internal diseases as renal dysfunction. methods: in this case series study, 59 patients poisoned with oral hypo...

acrylamide (aa) is an important industrial chemical agent that is mainly used in the production of polymers and copolymers. recently it has been attention because of its production in the diet at high-temperature (>120 ºc) processes such as cooking, frying, toasting, roasting or baking of high carbohydrate foods. according to high exposure to acrylamide, recognition of its toxic effect is neces...