During terminal differentiation, mammalian epidermal lipids undergo striking changes in both composition and distribution. Phospholipids and neutral lipids are replaced by a mixture of ceramides and neutral lipids organized in intercellular lamellar bilayers. Whether all of these lipids and/or whether specific lipid classes regulate permeability barrier function is not known. When hairless mice...

The outermost 10-20 µm of the epidermis, the stratum corneum (SC), consists of flat, dead cells embedded in a matrix of intercellular lipids. These lipids regulate cutaneous water loss (CWL), which accounts for over half of total water loss in birds. However, the mechanisms by which lipids are able to regulate CWL and how these mechanisms change with depth in the SC are poorly understood. We us...

The effects of 3-nitro-2,5-dichlorobenzoic acid (dinoben) and 3-amino-2,4-dichlorobenzoic acid (chloramben) on lipid formation and on the incorporation of various substrates into lipids by intact seeds and subcellular fractions of germinating soybean (Glycine max [L.] Merr. ;Amsoy') were studied. Dinoben (20 mug/ml) inhibited synthesis of total lipids 67%, neutral lipids 73%, glycolipids 51%, a...

The lipids of Treponema innocens, type strain B256, formerly considered a nonpathogenic isolate of T. hyodysenteriae, have been analyzed and compared with the lipids of T. hyodysenteriae. The lipids of T. innocens comprised 16% of the cell dry weight. Polar lipids amounted to about two-thirds of the total lipids and consisted of 61.9% phospholipids and 38.1% glycolipid. Neutral lipids consisted...

ROSENTHAL, J., A. ANGEL, AND J. FARKAS. Metabolic fate of leucine: a sign$kant sterol precursor in adipose tissue and muscle. Am. J. Physiol. 226(2) : 411-418. 1974.-The quantitative significance of muscle and adipose tissue as extrahepatic sites of leucine metabolism was studied. The rate of leucine conversion to either CO* or total lipid expressed per gram wet weight of tissue was adipose tis...

OBJECTIVE To describe the most representative food items regarding the total intake of energy, carbohydrates, proteins and lipids in children with ages between 7 and 10 years. METHODS A list was prepared with all food intake and quantities, and the diet composition in relation to energy and macronutrients was calculated. The list was based on information provided by a 3-day-Food Diary complet...

Glyceryl ethers are present in most mammalian tissues (17, 21) but have until recently been isolated from only a few anaerobic microorganisms (1, 4, 8, 9). Recently, Kamio et al. (12) have shown that these lipids are present in a number of anaerobic soil microorganisms, and Meyer and Meyer (14) have reported alk-1'-enyl glyceryl ethers (plasmalogens) in Treponema pallidum (Reiter) isolated from...