Oxidative stress is involved in a variety of diseases. Prospective studies investigating the relationship between oxidative stress biomarkers and the status and development of colorectal cancer (CRC) are scarce; previous studies have failed to establish a relationship between the serum total oxidant/antioxidant status and CRC. Therefore, we compared the total serum oxidant/antioxidant levels of...

1. Rice-Evans C, Miller NJ. Total antioxidant status in plasma and body fluids. Methods Enzymol 1994;234:279–93. 2. Cao G, Alessio CP, Cutler RG. Oxygen-radical absorbance capacity assay for antioxidants. Free Radic Biol Med 1993;14:303–11. 3. Benzie IFF, Strain JJ. The ferric reducing ability of plasma (FRAP) as a measure of “antioxidant power”: the FRAP assay. Anal Biochem 1996;239: 70–6. 4. ...

PURPOSE To analyze oxidative stress in primary open-angle glaucoma (POAG). MATERIAL AND METHODS A case-control study including 90 eyes of 90 patients who needed antiglaucomatous surgery in the course of POAG (glaucoma group, n=50) and from patients who were operated of nonpathologic cataracts (cataract group, n=40). Free radical formation via lipid peroxidation by malondialdehyde-thiobarbitur...

BACKGROUND Subjects consuming protein-restricted diets, such as patients with phenylketonuria (PKU) or milder hyperphenylalaninemias (HPAs) are at risk of selenium deficiency. Selenium is a cofactor of the antioxidant enzyme glutathione peroxidase and of the thyroid hormone converting enzyme thyroxine deiodinase. OBJECTIVE Our goal was to investigate the effects of low plasma selenium on anti...

OBJECTIVE To investigate the status of the oxidant/antioxidant balance in patients with multiple myeloma compared to healthy controls. MATERIALS AND METHODS This study was conducted on 40 multiple myeloma patients and 40 healthy controls of matched age and sex. Serum total thiol, oxidative stress index (OSI), total oxidant status (TOS), and total antioxidant status (TAS) were measured using c...

This study was designed to investigate the in vitro and in vivo antioxidant activities of inulin. The in vitro assays demonstrated that the antioxidant activities of inulin, including the DPPH radical scavenging activity, ABTS scavenging activity and ferric reducing power, were weak and significantly lower than those of Vitamin C (P < 0.05). The influence of dietary supplementation with inulin ...

cyfluthrinm[cyano[4-fluoro-3-phenoxyphenyl]-methyl-3-[2,2-dichloroethenyl]-2,2-dimethyl-cyclo propane carboxylate] is a synthetic pyrethroid insecticide, that has both contact and stomach poison action. the present study evaluated the long-term toxic effects of cyfluthrin on antioxidant status in buffalo calves. oral administration of cyfluthrin at a dose rate of 10 and 20 mg/kg/d for 11 consec...

Nephrotic patients show various abnormalities in protein kinetics. Plasma albumin levels and the total plasma albumin pool are reduced. Nephrotic syndrome is a consequence of an imbalance between oxidant and anti-oxidant activity. Oxidative damage has been proposed as one of the possible mechanism involved in the Nephrotic syndrome. Therefore, this study was carried out to investigate oxidant a...

grape seed proanthocyanidin extract (gspe) has a broad spectrum of biologic properties against oxidative stress. this study aimed to investigate the effects of gspe on biochemical factors and antioxidant enzymes of erythrocyte in diabetic rats. diabetes was induced through single injection of streptozotocin (50 mg.kg-1, i.p). forty male sprague-dawley rats were divided into four groups: group 1...

Oxidative damage by free radicals has been implicated in the pathogenesis of vascular disease in diabetes and hypertension. In the present study, the total antioxidant status in diabetic and hypertensive rats before and after treatment with garlic (Allium sativum) was determined. The total serum antioxidants were measured by a modified method reported earlier by Miller and coworkers. The reprod...