This research was designed to study the effect of bitter almond oil on the healing of open skin wounds in rats. Thirty female adult rats were randomly divided into experimental (n=15) and control (n=15) groups. Under general anesthesia and sterile conditions, one quadrangular (surface area=22 mm) full thickness skin wound was made on the dorsum of each rat. The day of surgery was considered as ...

Scalp psoriasis with alopecia is a rare cutaneous reaction to tumor necrosis factor alpha antagonists. This reaction often reverses with discontinuation of the offending drug and initiation of topical treatments; however, irreversible hair loss may occur if a scarring alopecia develops. We describe a woman with Crohn's disease who developed scalp psoriasis and alopecia secondary to infliximab. ...

Natural plant extracts often contain compounds that are useful in pest management applications. The essential oil of Eupatorium capillifolium (dog-fennel) was investigated for antifungal and insecticidal activities. Essential oil obtained by hydrodistillation of aerial parts was analyzed by gas chromatography (GC) and gas chromatography-mass spectrometry (GC/MS). The major components were deter...

Essential oils from anise, hyssop, thyme, ginger, camomile and sandalwood were screened for their inhibitory effect against herpes simplex virus type 2 (HSV-2) in vitro on RC-37 cells using a plaque reduction assay. Genital herpes is a chronic, persistent infection spreading efficiently and silently as sexually transmitted disease through the population. Antiviral agents currently applied for t...

PURPOSE The aim of the present research was to formulate a transparent microemolsion as a topical delivery system for tretinoin for the treatment of acne. METHODS Microemulsion formulations prepared by mixing appropriate amount of surfactant including Tween 80 and Labrasol, co-surfactant such as propylene glycol (PG) and oil phase including isopropyl myristate - transcutol P (10:1 ratio). The...

Essential oils of Eulcalyptus globulus, Lavender officinalis, Rosemarinus officinalis, and Thymus vulgaris were examined for their repellent activities against Culex pipiens pallens. All 4 essential oils effectively repelled adult mosquitoes on hairless mice. Essential oil of T. vulgaris (thyme) had potent repellent activity within the tested materials, with a protection rate of 91% at a concen...

BACKGROUND The increased incidence of inflammatory diseases has necessitated the need to search for new topical dosage form of dexamethasone. OBJECTIVES The purpose of the present study was the preparation and evaluation of novel microemulsion as a topical delivery system for dexamethasone by mixing appropriate amount of surfactant including Tween 80 and Labrasol, cosurfactant such as capryol...

Two ladybeetles, Cycloneda sanguinea and Harmonia axyridis, were exposed in the laboratory to eight fungicide formulations commonly used in citrus production in Florida. Both benomyl and the combination of copper and petroleum oil proved toxic to larvae of C. sanguinea that were exposed to concentrations corresponding to recommended field rates, either as leaf residues or in topical spray appli...

This work studied safety and antifungal activity of ozonized sunflower oil (AMO3) against dermatophytes. AMO3 was prepared through a new original process that modifies the oil before ozonation by alcoholic catalytic esterification. Susceptibility was studied in 41 dermatophytes by agar diffusion and broth microdilution tests. The experimental model to assess the topical safety of the oil includ...