Agel bait-resistantGerman cockroach,Blattella germanica (L.), strainCincywas collected in Cincinnati, OH. This strain exhibited a high level of behavioral resistance to Avert (0.05% abamectin) and Maxforce FC (0.01% Þpronil) gel baits. Topical application assays indicated moderate levels of physiological resistance of the Cincy strain to abamectin and Þpronil. Resistance ratios (based on LD50 v...

A novel stability-indicating RP-HPLC method was developed for the simultaneous estimation of clindamycin phosphate (hydrophilic), adapalene (hydro-phobic), phenoxyethanol, and methylparaben in topical gel formulations. Optimum chromatographic separation among the analytes and stress-induced degradants peaks was achieved on the XBridge C18 (50 × 4.6 mm, 3.5 µm) column using a mobile phase consis...

The present study aims to evaluate the topical anti-inflammatory activity of "Pinda thailam", a herbal gel formulation containing aqueous extract of roots of Rubia cordifolia (Rubiaceae) and Hemidesmus indicus (Asclepiadaceae) which are known for their anti-inflammatory activity using the technique of carrageenin induced paw oedema in albino rats. The herbal gel formulation showed significant a...

We report results of a randomized, vehicle-controlled, bilateral comparison pilot study of bexarotene gel 1% with narrowband UVB (NBUVB) phototherapy for moderate to severe psoriasis. In all, 9 patients applied drug or vehicle gel to comparable target lesions up to twice daily for 10 weeks. NBUVB was initiated 2 weeks after topical therapy began. Limitations include small sample size and interi...

The gastric irritant effects of peroral lornoxicam can be attenuated using skin as the route of administration. The present work was focused on the development, characterization, ex vivo skin permeation and skin targeting behaviors of lornoxicam-loaded solid lipid nanoparticles (SLN). Lornoxicam loaded SLN was prepared by emulsification solvent evaporation technique. The particle size and polyd...

Two techniques for anaesthetising the nose before fibreoptic bronchoscopy have been compared. Fourteen of 16 patients given lignocaine spray found it unpleasant, compared with three of 20 patients given lignocaine gel. The two forms of local anaesthetic were found to be equally effective. Lignocaine gel is therefore recommended for topical nasal anaesthesia before fibreoptic bronchoscopy.

aloe littoralis baker (asphodelaceae family) is a well known plant in southern parts of iran. because of its use in iranian traditional medicine as a wound-healing agent, the present study was carried out to investigate anti-inflammatory and wound healing activities of this plant in wistar rats. a. littoralis raw mucilaginous gel (alrmg) and also two gel formulations prepared from the raw mucil...

Background and objectives: Dorema ammoniacum gum resin is used in Iranian traditional medicine for different indications including inflammatory diseases which are on the rise. Considering the important role of inflammation in different diseases, in the present study, we aimed to investigate the in vivo anti-inflammatory activity and skin toxicity of Dorema ammoniac...