The nuclear-electronic orbital ~NEO! method for the calculation of mixed nuclear-electronic wave functions is presented. Both electronic and nuclear molecular orbitals are expressed as linear combinations of Gaussian basis functions. In the NEO-HF ~Hartree-Fock! method, the energy corresponding to the single-configurational mixed nuclear-electronic wave function is minimized with respect to the...

Sex chromosomes originated from autosomes but have evolved a highly specialized chromatin structure. Drosophila Y chromosomes are composed entirely of silent heterochromatin, while male X chromosomes have highly accessible chromatin and are hypertranscribed as a result of dosage compensation. Here, we dissect the molecular mechanisms and functional pressures driving heterochromatin formation an...

We compared the Neo-Sensitabs tablet assay to both reference M27-A2 broth microdilution and M44-A disk diffusion methods for testing susceptibilities of 110 isolates of Candida spp. and Cryptococcus neoformans to amphotericin B, caspofungin, fluconazole, itraconazole, and voriconazole. Neo-Sensitabs assay inhibition zone diameters in millimeters on three agars (Mueller-Hinton agar supplemented ...

The neo (neomycin phosphotransferase) gene is widely used as a selection marker in the production of genetically engineered animals and plants. Recent attention has been focused on safety concerns regarding neo transgene expression. In this study, neo transgenic and non-transgenic piglets were randomly assigned into Group A and Group B to evaluate effects of neo transgene by studying changes in...

neo-ottomanism in recent decades has been among the most controversial political debates in related academies and literature. frequent references to it by turkish officials in recent years, multiplied its importance in international relations. the term obviously owes its significance to the ottoman empire era, and accordingly, a sufficient analysis on the challenges of the empire during its las...

This text aims to question the current “post-Fordist” model, after defining the former Fordism, and showing some latter configurations of “post-Fordism” in Britain, France, Germany and Japan. The compilation of knowledge concerning the organization of work was developed, first of all, by F. W. Taylor, based on technical and scientific methods and on the division of work. Nowadays, many expressi...

The study of asteroid families has provided tremendous insight into the forces that sculpted the main belt and continue to drive the collisional and dynamical evolution of asteroids. The identification of asteroid families within the NEO population could provide a similar boon to studies of their formation and interiors. In this study we examine the purported identification of NEO families by D...

Using a small near-Earth object (NEO) to impact a larger and potentially threatening NEO has been suggested as an effective method to avert a collision with Earth. This paper develops a procedure for analysis of the technique for specific NEOs. First, an optimization method is used to select a proper small body from the database. Some principles of optimality are achieved with the optimization ...

This study evaluates the validity of derived measures of the psychopathic personality traits of Fearless Dominance and Impulsive Antisociality from the NEO Personality Inventory-Revised (NEO-PI-R; Costa & McCrae, 1992) using data from the Collaborative Longitudinal Personality Disorders Study (baseline N = 733). These 3 issues were examined: (a) the stability of the measures over a 10-year inte...

Retroviral gene expression is inhibited in embryonal carcinoma (EC) cells. We have constructed a recombinant retroviral vector that is capable of expressing the neomycin-resistance (neo) gene in EC cells. The critical modification that permits expression of the neo gene is the insertion of a composite simian virus 40 early gene-herpes simplex virus type 1 thymidine kinase gene (SVtk) promoter 3...