نتایج جستجو برای: tnp

تعداد نتایج: 816  

Journal: :The Journal of Experimental Medicine 1985
I V Hutchinson W H Barber P J Morris

Suppressor T cells, activated by injection of trinitrobenzene sulphonic acid in DA rats, prevented rejection of LEW kidney allografts in a donor-specific manner when adoptively transferred into syngeneic recipients along with trinitrophenyl (TNP)-haptenated LEW alloantigen. TNP-haptenated third-party alloantigen was ineffective in this system. The donor-specific suppression was dependent, too, ...

Alborz Jafaee Sough, Erfan Daneshi, Forouzan Absalan, Layasadat Khorsandi, Mahmoud Orazizadeh, Sadegh Saremy,

Introduction: In the present study, we assessed the effects of β-carotene on Titanium oxide Nanoparticle (TNP) induced mouse Spermatozoon Stem Cells (SSCs) apoptosis, at molecular level.  Methods: After isolation from cryptorchid mouse testis and characterization, spermatogonial stem cells were divided into four groups. In the control group, spermatogonial cells were cultured in &alp...

Journal: :Journal of immunology 1998
S Gustavsson S Hjulström-Chomez B M Lidström N Ahlborg R Andersson B Heyman

In murine in vivo systems, Ags administered in physiologic solutions together with specific IgE induce a significantly higher Ab response than Ags administered alone. In vitro, IgE in complex with Ag enhances B cell-mediated presentation of the Ag to T cells. Both phenomena require an intact low affinity receptor for IgE (Fc epsilon RII/CD23), suggesting that the effect on in vivo Ab responses ...

Journal: :Nucleic acids research 2004
Brandon Ason William S Reznikoff

Transposition causes genomic instability by mobilizing DNA elements. This phenomenon is mechanistically related to other DNA rearrangements, such as V(D)J recombination and retroviral DNA integration. A conserved active site architecture within the transposase/integrase superfamily catalyzes these distinct phenomena. The Tn5 transposase (Tnp) falls within this protein class, and many intermedia...

Journal: :Cellular immunology 1975
S P Lerman T J Romano J J Mond M Heidelberger G J Thorbecke

Trior dinitrophenylated pneumococcal polysaccharide type 111 ( T N P or DNPS I I I ) ) induced a primary 19s anti-TNP response without generating immunological niemory to the hapten in LAFI mice. Hapten-hemocyanin (TNP-KLH) or hapten conjugates of B . a6ortirs organisms (DNP-BA) induced both 19s and 7s primary responses and memory to the hapten. Spleen cells from mice immunized with T N P K L H...

Journal: :Kidney international 1994
T Fulpius T Berney R Lemoine Y Pastore L Reininger G Brighouse S Izui

We have previously shown that murine IgG3 monoclonal autoantibodies with cryoglobulin activity, derived from lupus-prone mice, are able to induce glomerular lesions resembling the "wire-loop" lesion typically described for human lupus nephritis. In the present study, we have further assessed the nephritogenic potential of four IgG3 anti-hapten, trinitrophenyl (TNP), monoclonal antibodies (mAb) ...

Journal: :Oncotarget 2015
Michael Bruns Jara Wanger Olaf Utermöhlen Wolfgang Deppert

In Simian virus 40 (SV40) transgenic BALB/c WAP-T mice tumor development and progression is driven by SV40 tumor antigens encoded by inducible transgenes. WAP-T mice constitute a well characterized mouse model for breast cancer with strong similarities to the corresponding human disease. BALB/c mice mount only a weak cellular immune response against SV40 T-antigen (T-Ag). For studying tumor ant...

Journal: :The Journal of Experimental Medicine 1977
W E Biddison H R Snodgrass J Bennink R B Effros P C Doherty

Cytotoxic thymus-derived lymphocytes generated after interaction with trinitrophenyl (TNP)-substituted or virus-infected cells only lyse H-2 compatible target cells modified with the component used to immunize (TNP or virus). Prior saturation of TNP-reactive sites inhibits neither the infectivity of influenza A viruses, nor the capacity of infected cells to develop antigenic changes recognized ...

Journal: :The Journal of Experimental Medicine 1980
R B Levy G M Shearer

An H-2K/IA recombinant mouse strain was used to map the genes within the H-2 complex which determine the ability to respond in cell-mediated lympholysis (CML) to low doses of trinitrophenyl-self (TNP-self). It was found that gene(s) which map to the K region are involved in regulation of CML response to low-dose TNP-self. It was also found that CML response to TNP recognized in association with...

Journal: :Hpb 2021

Introduction: Surgery is standard treatment for pancreatic-neuroendocrine-tumors (TNP) although it occasionally associated with high-rates of morbid-mortality. Radiotherapy can be an effective alternative in selected patients. Our objective to evaluate the efficacy SBRT (Stereotactic-body-radiation-therapy) as a radical TNP. Materials and methods: Between December 2017 November 2020, we prospec...

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