The gradient monotonicity of existing tumor, node, metastases staging systems for colorectal cancer is unsatisfactory. Our proposed T-plus staging system strengthens weighting of the T stage. In this study, applicability of the T-plus staging system was verified with data of a Chinese colorectal cancer center. Records of 2080 nonmetastatic, advanced cancer patients undergoing colorectal cancer ...

O'Connell et al. (1) showed that the stage groupings in the newer sixth edition of the tumor-lymph node-metastasis (TNM) staging system more distinctly stratify survival than the fi fth edition (2 , 3). However, survival was worse with T4N0M0 (stage IIB) than with T1-2N1M0 (stage IIIA) disease. Review of 351 000 colon cancer case records in the National Cancer Data Base confi rms this fi nding ...

BACKGROUND Mucosal melanoma (MM) of head and neck (H&N) is a rare entity with a quite poor prognosis. Ballantyne's staging system has been commonly used since 1970. In the 7th edition of the AJCC Staging Manual a new chapter for the staging of TNM Classification system for mucosal melanoma (MM) of the head and neck (H&N) has been introduced to reflect the particularly aggressive biological beha...

INTRODUCTION Thrombocytosis has been identified as an unfavorable prognostic factor in several types of cancer. This study aimed to evaluate the prognostic value of pretreatment platelet count in association with the TNM staging system and therapeutic regimens in patients with nasopharyngeal carcinoma (NPC). METHODS A total of 2,626 patients with NPC were retrospectively analyzed. Platelet co...